Evaluation of Progression of Myopia in Children Treated With Vitamin B2 and Outdoor Sunlight Exposure

Phase 2

Suspended

• Conditions: Axial Myopia; Refractive Errors

• Registration Number: NCT03552016
• Lead Sponsor: University of Missouri-Columbia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-5-28
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Suspended
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Inclusion Criteria:<br><br> - Healthy children ages 6-12 years old with myopia more than 0.50 D and astigmatism no<br> more than 1.5 D.<br><br> - Caretakers who choose to enroll their child in the study must agree to participate<br> in the study on their own will after knowledge of potential alternatives (spectacle<br> correction, orthokeratology, atropine eye drops, etc.) are explained to the<br> patient's caretaker.<br><br>Exclusion Criteria:<br><br> - Known allergy to riboflavin<br><br> - Birth history of premature birth<br><br> - Developmental delay or other neurological or mental conditions<br><br> - Major systemic health problems<br><br> - Significant anisometropia more than 1.5 Diopters<br><br> - Any other eye condition which may complicate interpretation of data including:<br> congenital glaucoma, congenital cataract, ectatic corneal condition, amblyopia or<br> strabismus.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in cycloplegic refraction

Secondary Outcome Measures

Name	Time	Method
Change in axial length;Change in keratometry values;Change in uncorrected best visual acuity