A Comparative Randomized Control Study between Amlodipine and Cilnidipine in mild Hypertensive patients to evaluate the efficacy and safety of the two drugs in cardiology outpatient department of tertiary care hospital
Not Applicable
- Conditions
- Health Condition 1: null- Grade-I Hypertensive patients
- Registration Number
- CTRI/2018/08/015150
- Lead Sponsor
- RS Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1 Newly diagnosed case of gradeI hypertension
2 Adult age group from 18 yrs to 80 yrs
3 Patients willing to give written consent
4 Hypertensive patients without other co morbid factors like angina cardiac ischemia cerebrovascular disease peripheral vascular disease cardiac infarction renal disease preexisting edema corpulmonale anaemia hypoproteinemia nephrotic syndrome hepatic cirrhosis
Exclusion Criteria
1 Patients taking NSAIDS and Amantadine
2 Patients taking other anti hypertensive drugs
3 Pregnancy
4 Patients taking antipsychotic drugs
5 Patients taking drugs that cause Pedal Edema
6 Patients not responding in treatment during 2 weeks
7 Patients taking less than 30 percent of the tablets dispensed as study medication
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1 Changes Of systolic Blood Pressure From baseline to normal <br/ ><br> <br/ ><br>2 Changes Of Diastolic Blood Pressure From Baseline to normalTimepoint: 52 weeks after starting of treatment
- Secondary Outcome Measures
Name Time Method 1 Heart rate changes <br/ ><br>2 Changes in ecg <br/ ><br>3 Changes in estimated glomerular filtration rate <br/ ><br>4 Changes in albumin creatinine ratio <br/ ><br>5 Changes in echocardiography <br/ ><br>Timepoint: 52 weeks after starting of treatment