Idiographic study of Neurofeedback to Ameliorate Mood in the Elderly (i-NAME); A pilot study with six patients.

Withdrawn

Conditions: depression
major depressive disorder
10027946

Registration Number: NL-OMON43268

Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Withdrawn

Sex: Not specified

Target Recruitment: 6

Inclusion Criteria

- Age 60 years or over.
- Suffering from clinically relevant depressive symptoms defined as a score of 16 or more on the Center for Epidemiological Studies Depression Scale (CES-D) (Radloff, 1977; Eaton et al, 2004).
- Having met the criteria of Diagnostic and Statistical Manual of Mental Disorders (DSM-5) for a major depressive disorder (MDD) within the past 12 months (but no current MDD) as established with the Mini International Neuropsychiatric Interview (version 5.0).
- Right handedness.
- Giving informed consent after oral and written information about the study

Exclusion Criteria

- Insufficient command of the Dutch language.
- Not capable of daily neurofeedback training.
- Major psychiatric comorbidity other than an affective disorder (encompassing mood-, anxiety or somatoform disorders).
- An established (or suspected) diagnosis of dementia or a neurodegenerative disorder.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Variance in depressive symptoms explained by changes in NF induced frontal<br /><br>alpha lateralization within individuals.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- Feasibility and patient burden of both NF training and data collection from a<br /><br>patient perspective<br /><br>- Compliance to NF training and study procedures<br /><br>- Psychopathology at baseline, and after 4, 8 and 12 weeks.</p><br>