NCT05612048进行中（未招募）不适用
Pilot Study of Dental Erosion as a Non-invasive Biomarker of Esophagogastric Cancer
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 174
- 试验地点
- 1
- 主要终点
- The incidence of dental erosions
研究概览
简要总结
The researchers are doing this study to find out more about what may lead to the loss of tooth enamel (the thin outer covering of the tooth) and how often it happens in people with esophagogastric cancer, colorectal cancer, pancreatic cancer, breast cancer, head and neck cancer, or non-small cell lung cancer, or a healthy volunteer.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subject is willing and able to provide written informed consent.
- •Patients with a history of esophagogastric, HNSCC, PDAC, CRC, or NSCLC or healthy controls
- •Patients must be able to fully comprehend and complete the survey and be willing to have pictures taken of their teeth with a camera or intra-oral camera.
- •Patients must be able to understand English language or have access to adequate translation services.
- •Age ≥ 18 years old.
排除标准
- •Subjects without evaluable molars or with significant molar dental work precluding dentists from assessing enamel status, Note: evaluable is defined as having bilateral assessable mandibular molars, or erosions present in the remaining assessable quadrants.
- •For healthy controls only, patients cannot have a non-skin cancer history nor presenting for a procedure evaluating reflux symptoms.
结局指标
主要结局
The incidence of dental erosions
时间窗: 1 year
scored with a modified BEWE index.
次要结局
未报告次要终点
研究者
研究点 (1)
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