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Clinical Trials/NCT06447142
NCT06447142
Completed
Not Applicable

Comparison of the Open Kinetic Chain and Closed Kinetic Chain Strengthening Exercises on Pain, Function, and Health-related Quality of Life in Degenerative Meniscus Tears

Istanbul University - Cerrahpasa1 site in 1 country56 target enrollmentStarted: June 10, 2024Last updated:

Overview

Phase
Not Applicable
Status
Completed
Sponsor
Istanbul University - Cerrahpasa
Enrollment
56
Locations
1
Primary Endpoint
Knee Injury and Osteoarthritis Outcome Score (KOOS)

Overview

Brief Summary

This randomized-controlled trial aims to compare the effect of open kinetic chain and closed kinetic chain strengthening exercises on pain, function, and health-related quality of life in degenerative meniscus tears.

Detailed Description

Patients with degenerative meniscus tears between the ages of 35 and 65 will be randomly divided into two groups: Group 1 (open kinetic chain strengthening exercises) and Group 2 (closed kinetic chain strengthening exercises). Interventions will be applied for 16 sessions (twice a week for 8 weeks). The patients will be assessed at baseline and at the end of the 8-week intervention. The pain during activity, at rest, and at night will be assessed with the Visual Analog Scale (VAS). Active range of motion will be assessed with a digital goniometer. Isometric muscle strength will be measured with a handheld dynamometer. The functional status and symptoms will be evaluated by the Knee Injury and Osteoarthritis Outcome Score (KOOS) and Lysholm Knee Scoring Scale. Health-related quality of life will be assessed with the Short Form-12 (SF-12).

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Participant, Outcomes Assessor)

Eligibility Criteria

Ages
35 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Being aged between 35 and 65 years
  • Having the degenerative meniscus tear in at least one knee
  • Having body mass index in the range of 18-30 kg/m2
  • Feeling the pain that lasts for at least 2 months
  • Having grade 1 or grade 2 degenerative meniscal tear diagnosed by an orthopedic specialist according to the MRI results
  • Access to the internet via a computer or smartphone
  • Ability to read and write in Turkish

Exclusion Criteria

  • Having undergone arthroscopic partial meniscectomy surgery due to degenerative meniscal tear
  • Participating in a physiotherapy program for degenerative meniscal tear in the last 12 weeks
  • Have received steroid injections in the last 6 months
  • Accompanying conditions such as injury to the surrounding ligaments, congenital anomaly in the affected knee, coxarthrosis and spinal stenosis
  • Presence of any systemic disorder that may affect assessment parameters
  • Any health condition that may prevent participation in physical activity or an exercise program (e.g., severe cardiovascular, respiratory, neurological, or musculoskeletal disorders)
  • Failure to cooperate with assessments

Outcomes

Primary Outcomes

Knee Injury and Osteoarthritis Outcome Score (KOOS)

Time Frame: Baseline

Short-term and long-term symptoms and function will be assessed with the Knee injury and Osteoarthritis Outcome Score (KOOS) that is developed as an extension of the WOMAC Osteoarthritis Index. The score is a percentage score from 0 to 100, 0 representing extreme problems and 100 representing no problems.

Secondary Outcomes

  • Active Range of Motion(At the end of 8-week intervention)
  • Muscle Strength(At the end of the 8-week intervention)
  • Lysholm Score(At the end of the 8-week intervention)
  • Short Form-12 (SF-12)(At the end of the 8-week intervention)
  • Knee Injury and Osteoarthritis Outcome Score (KOOS)(At the end of 8-week intervention)
  • Visual Analogue Scale (VAS)(At the end of 8-week intervention)

Investigators

Sponsor
Istanbul University - Cerrahpasa
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Tansu Birinci

Principal Investigator

Istanbul University - Cerrahpasa

Study Sites (1)

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