NL-OMON21949Not yet recruitingNot Applicable
Effects of rosuvastatin on the pharmacokinetics of imatinib.
Prof. Dr. J. VerweijErasmus MC - Daniel den Hoed Cancer CenterGroene Hilledijk 3013075 EA Rotterdam0 sites12 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 12
Study Overview
Brief Summary
Eechoute et al. Environmental and genetic factors affecting transport of imatinib by OATP1A2. Clin Pharmacol Ther. 2011;89(6):816-20
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •1.Histological or cytological confirmed diagnosis of any form of irresectable and/or metastatic GIST, which is already treated with imatinib for a consecutive period of at least 4 weeks;
- •2.Age ³ 18 years;
Exclusion Criteria
- •1.Pregnant or lactating patients; patients with reproductive potential must use a reliable method of contraception (excluding oral contraceptives), if required;
- •2.Serious illness or medical unstable condition requiring treatment, symptomatic CNS-metastases or history of psychiatric disorder that would prohibit the understanding and giving of informed consent;
Investigators
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