Morphine versus Ketamine for traumatic pain in the prehospital setting

Completed

• Conditions: Moderate to Severe traumatic Pain; Musculoskeletal - Other muscular and skeletal disorders; Injuries and Accidents - Fractures

• Registration Number: ACTRN12607000441415
• Lead Sponsor: Prof. Peter Cameron

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-08-31
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

Attended by participating ambulance crew
Patient conscious (GCS=15), speaking and able to rate their pain using the Verbal Numerical Rating Scale (VNRS) Moderate to Severe pain due to trauma defined as VNRS of 5 or greater.

Exclusion Criteria

Known allergy to ketamine hydrochloride or morphine sulphate
Pregnant or lactating women
Ischameic chest pain, acute pulmonary oedema and/or severe hypertension (Systolic Blood Pressure>180 mmHg)
Head injury with a history of loss of consciousness or Glasgow Coma Scale<15
Inability to obtain venous access
Presumed intoxication with alcohol or illicit substances

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in pain Verbal Numeric Rating Scale (VNRS)[On arrival at a receiving hospital Emergency Department]

Secondary Outcome Measures

Name	Time	Method
Chronic pain / functionality score[At 6 months];Incidence of adverse events, such as excessive sedation, blood pressure changes, arrhythmias, nause and vomiting[Until arrival at a receiving Emergency Department];Total dose of opioid required for pain relief[On arrival at a receiving hospital Emergency Department]