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Clinical Trials/NCT05215626
NCT05215626
Completed
Not Applicable

Post-market Clinical Follow-up Study to Provide Safety, Performance and Clinical Benefits Data of the Zimmer® Reconstruction System (Implant and Instrumentation) - A Retrospective Consecutive Series Study

Zimmer Biomet1 site in 1 country78 target enrollmentAugust 1, 2022

Overview

Phase
Not Applicable
Intervention
Patients implanted with the Zimmer Reconstruction System
Conditions
Acetabulum Fracture
Sponsor
Zimmer Biomet
Enrollment
78
Locations
1
Primary Endpoint
Performance: Fracture Healing
Status
Completed
Last Updated
last month

Overview

Brief Summary

The study is a monocentric, retrospective, non-randomized, non-controlled and consecutive series post-market study. The purpose of this study is to confirm safety, performance and clinical benefits of the Reconstruction System (implants and instrumentation) when used for temporary internal fixation and stabilization of fractures during the normal healing process.

The primary objective is the assessment of performance by analyzing fracture healing.

The secondary objectives are the assessment of safety by recording and analyzing the incidence and frequency of complications and adverse events. Relation of the events to implant, instrumentation and/or procedure should be specified. Subjects' outcomes will also be assessed.

Detailed Description

The Reconstruction System is especially used to stabilize pelvic ring and acetabulum fractures. One site will be involved in this study. The aim is to include a maximum of 83 consecutive series cases who received the Zimmer Reconstruction System at the Azienda Ospedaliero Universitaria Senese (Siena, Italy) between 2010 and 2018. All potential study subjects will be required to participate to the Informed Consent process. Baseline data from the preop, intraop, immediate post-op and last consultation visit will be available in medical notes and collected retrospectively. In addition, any complications since the last consultation visit at the clinic and information about the treatment of the complications will also be collected retrospectively.

Registry
clinicaltrials.gov
Start Date
August 1, 2022
End Date
December 12, 2024
Last Updated
last month
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients having received the Zimmer Reconstruction System for temporary internal fixation and stabilization of fractures during the normal healing process

Exclusion Criteria

  • Off-label use
  • Patients under the age of 18
  • Severely comminuted fractures in which bone fragments are too small or numerous to adequately fix or maintain a reduced position
  • Infection
  • Metal sensitivity or intolerance
  • Severe osteopenia and/or osteoporosis, or in the presence of marked or rapid bone absorption, metabolic bone disease, cancer, or any other tumor-like condition of the bone which may compromise fixation
  • Sternal or spinal fractures
  • Anatomical location in which the device would interfere with nerves, blood vessels, or other vital structures
  • Patients with inadequate soft tissue coverage at the implant site

Arms & Interventions

Patients implanted with the Zimmer Reconstruction System

Patients implanted with the Zimmer Reconstruction System

Outcomes

Primary Outcomes

Performance: Fracture Healing

Time Frame: Mean time of 1.99 years after the surgery

Performance will be assessed by analyzing fracture healing radiographically by X-rays.

Secondary Outcomes

  • Product Safety(Mean time of 1.99 years after the surgery)
  • Harris Hip Score(Mean time of 1.99 years after the surgery)

Study Sites (1)

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