Evaluation of cytology-based tumor resection for the surgical treatment of head and neck squamous cell carcinoma (HNSCC) patients

Not Applicable

Recruiting

• Conditions: C06.9; C10.9; Mouth, unspecified; Oropharynx, unspecified

• Registration Number: DRKS00013507
• Lead Sponsor: niversitätsklinikum des SaarlandesKlinik für HNO-Heilkunde

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-12-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

cT1-2 squamous cell carcinoma of the oral cavity or the oropharynx (tonsil, base of tongue, soft palate); swab cytology feasible in an outpatient setting; planned surgical treatment; no necessarity of a plastic defect coverage by a free or pedicled flap transplant; signed informed consent; Age of 18 years or higher and unlimited legal capacity

Exclusion Criteria

Primary tumor in a region outside of the oral cavity or oropharynx; cT3 or higher staged Tumors; no clinical evidence for a malignant disease; swab cytology not feasible in an outpatient setting; no planned surgical treatment; necessarity of a plastic defect coverage with a free or pedicled flap transplant; lack of signed informed consent; age < 18 years or limited legal capacity; pregnancy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
time span between clinical diagnosis and definitive surgical treatment

Secondary Outcome Measures

Name	Time	Method
Overall survival, progression free survival (5 years follow-up), whole time span of treament, diagnostic sensitivity of liquid-based cytology for the diagnosis of HNSCC