Multicenter Observational Study on the Prevalence of Inappropriate Prescribing in Elderly Patients At Admission and Discharge from a Hospital Ward Using the STOPP/START Criteria
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Prescriptions
- Sponsor
- Regione del Veneto - AULSS n. 7 Pedemontana
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Prevalence of inappropriate prescribing in elderly patients at admission to an acute care hospital using STOPP/START criteria
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The management of pharmacotherapy in elderly patients is an increasingly critical aspect, as polypharmacy, combined with the pharmacokinetic and pharmacodynamic changes typical of aging, makes older adults more sensitive to the development of adverse reactions. This highlights the importance of appropriate use of pharmacotherapy that considers the risks and benefits of individual treatments. The aim of this study is to measure the prevalence of pharmacological appropriateness using the STOPP/START criteria (version 2) at admission and discharge from an acute geriatric ward, thereby evaluating the impact of hospitalization on medication prescribing.
Investigators
Luca Pellizzari
Specialist in Geriatrics
Azienda Ospedaliera Universitaria Integrata Verona
Eligibility Criteria
Inclusion Criteria
- •Patients aged ≥ 70 years admitted to a geriatric ward
- •Regardless of ethnicity, gender, or type of illness
- •Patients transferred from another ward
- •Patients admitted to another ward for support
Exclusion Criteria
- •Patients in the terminal phase (\<6 months life expectancy)
- •Criteria for exit from the study (Dropout):
- •Patients transferred to another hospital ward
- •Patients who have deceased
Outcomes
Primary Outcomes
Prevalence of inappropriate prescribing in elderly patients at admission to an acute care hospital using STOPP/START criteria
Time Frame: Data collected at time Day 0 is analyzed by day 4. Data collected at time Day 1 is analyzed by day 4
The analysis of inappropriate prescriptions at admission "Day 0" will be evaluated as a single outcome measure by aggregating data using the STOPP/START criteria. Specific assessments will be reported separately, as they involve different types of information and units of measure: * Prevalence of inappropriate prescriptions: The proportion of patients with prescriptions deviating from STOPP/START criteria (%). * Characteristics of patient history: Data such as active and passive diseases (count), place of origin (categorical variable), reason for admission (categorical variable), and presence of ADL support (binary variable: Yes/No). * Clinical indicators: Charlson Comorbidity Index (numerical score), number of medications (count), presence of geriatric syndromes (binary variable: Yes/No). * Mobility status: Whether the patient is bedridden or ambulatory (categorical variable). * Hospitalization history: Number of admissions in the past year (count).
Secondary Outcomes
- Prevalence of inappropriate prescribing in elderly patients at discharge from an acute care hospital using STOPP/START criteria.(Data collected at time Day 0 is analyzed by day 4. Data collected at time Day 1 is analyzed by day 4)
- Percentage of cases in which inappropriate prescribing will be detected at admission and discharge(Data collected at time Day 0 is analyzed by day 4. Data collected at time Day 1 is analyzed by day 4)
- Association between the prevalence of inappropriate prescriptions and clinical variables, measured using univariate and multivariate regression.(Data collected at time Day 0 is analyzed by day 4. Data collected at time Day 1 is analyzed by day 4)