Randomized controlled trial of endoscopic ultrasound-guided liver biopsy versus percutaneous liver biopsy for adequate liver biopsy specime
Not Applicable
Recruiting
- Conditions
- Chronic liver disease
- Registration Number
- JPRN-UMIN000046965
- Lead Sponsor
- Kitasato University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Not provided
Exclusion Criteria
1) coagulopathy (INR of =or >1.5 and/or platelet count =or <50,000) 2) patients who are unable to discontinue anticoagulant and/or antiplatelet medication (excluding aspirin alone) 3) patients with liver cirrhosis 4) presence of clinically detectable ascites around the liver 5) presence of gastric varices 6) post-esophagogastric surgery (excluding distal gastrectomy) 7) pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acquisition rate of adequate liver biopsy specimen
- Secondary Outcome Measures
Name Time Method 1) number of needle passes needed to obtain adequate sample 2) number of complete portal tract obtained in a liver biopsy specimen 3) post-fix aggregate liver biopsy specimen length 4) post-fix longest liver biopsy specimen length 5) pain score 6) time for hospital stay per patient 7) adverse event