Antibody Profiles in Pemphigoid (APP)

Not Applicable

Suspended

• Conditions: Bullous pemphigoid; Skin and Connective Tissue Diseases

• Registration Number: ISRCTN23684477
• Lead Sponsor: niversity Hospitals of Leicester

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-08-27
• Last Update Posted: 24 August 2020
• Study Completion: 2021-08-05

Recruitment & Eligibility

• Status: Suspended
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

1. Willing and able to give informed consent for participation in the study.
2. Aged 18 years or above.
3. Clinical diagnosis of suspected bullous pemphigoid.
4. Direct immunofluorescence on skin biopsy (which is performed as part of usual care) demonstrating linear deposition of IgG and/or C3 at the basement membrane zone reported within 8 weeks of enrolment.
5. Able (in the Investigators’ opinion) and willing to comply with all study requirements.

Exclusion Criteria

1. Alternative diagnosis to bullous pemphigoid at review by a dermatologist.
2. Skin biopsy is judged to be contraindicated for clinical reasons by the Investigator.
3. Direct immunofluorescence of a skin biopsy fails to demonstrate linear deposition of IgG or C3 at the basement membrane zone within 8 weeks of enrolment.

Study & Design

• Study Type: Observational
• Study Design: Not specified