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Clinical Trials/NCT05422859
NCT05422859
Recruiting
Not Applicable

Mobile and Digital Application in Heart Failure Networks Berlin/Brandenburg

German Heart Institute3 sites in 1 country50 target enrollmentJuly 1, 2022
ConditionsHeart Failure

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Heart Failure
Sponsor
German Heart Institute
Enrollment
50
Locations
3
Primary Endpoint
Acceptance of the application
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

The MobiDig trial is designed to evaluate an implementation of a mobile phone application with secondary preventive/rehabilitative modules for patients with heart failure in certified Heart Failure Unit centers in Berlin and Brandenburg.

The aim is to evaluate the effect on quality of life, symptoms and the course of the disease. In addition, the acceptance, adherence and user behavior as well as the implementation potential for a permanent introduction of the application in national heart failure networks will be analyzed.

Registry
clinicaltrials.gov
Start Date
July 1, 2022
End Date
January 1, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
German Heart Institute
Responsible Party
Principal Investigator
Principal Investigator

Sabine Huebler

Head of Studienzentrale

German Heart Institute

Eligibility Criteria

Inclusion Criteria

  • Confirmed diagnosis of heart failure
  • Treatment in a certified Heart Failure Unit center in Berlin or Brandenburg
  • Written informed consent of the participants
  • User of a mobile device with an iOS operating system

Exclusion Criteria

  • Addiction or other illnesses that do not allow the participants to assess the nature and scope as well as possible consequences of participation or its scientific evaluation
  • insufficient knowledge of the German language, which is necessary to use the application

Outcomes

Primary Outcomes

Acceptance of the application

Time Frame: 3 months

The acceptence of the application will be measured by the User Experience Questionnaire. It consists of 9 items that can be rated on a 7-point Likert scale. -3 (fully agree with negative term) to +3 (fully agree with positive term). A higher total score means a better outcome.

Change in symptoms of heart failure

Time Frame: Baseline and 3 months

Symptoms of heart failure will be assessed by the New York Heart Association functional class. Consisting of four classes (I-IV), the higher, the worse the outcome.

Change in six-minute walk distance

Time Frame: Baseline and 3 months

Functional capacity will be assessed by the 6-minute walk test

Length of hospitalizations

Time Frame: 3 months

Length of in-hospital stay of hospitalizations for heart failure will be assessed.

Patient reported outcomes

Time Frame: Baseline and 3 months

Health-related quality of life will be measured by the "Patient Related Outcome and Measurement Information System" (PROMIS) test. Including 23 items that will be analyzed via Likert scale 1 (impossible/never) to 5 (no limitations/very good). A higher score means a better outcome.

Change in daily walking distances

Time Frame: Baseline and 3 months

Functional capacity will be assessed by the steps taken within 24 hours (pedometry).

Change in quality of life

Time Frame: Baseline and 3 months

Quality of life measured by Kansas City Cardiomyopathy Questionnaire using the validated 12-item version which has been described by Spertus et Jones (doi: 10.1161/CIRCOUTCOMES.115.001958.) A higher score means a better outcome.

Change in heart failure biomarker

Time Frame: Baseline and 3 months

Heart failure severity will be assessed by the biomarker NT-proBNP.

Number of hospitalizations

Time Frame: 3 months

Number of hospitalizations for heart failure will be assessed.

Study Sites (3)

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