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Efficacy of luseogliflozin for fattty liver with diabetes mellitus

Not Applicable
Recruiting
Conditions
fatty liver with type 2 diabetes mellitus
Registration Number
JPRN-UMIN000031694
Lead Sponsor
Fujita Health University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

1. Using insulin 2. Has hypersensitivity to luseogliflozin 3. Has history of hepatitis B, hepatitis C and autoimmune hepatitis 4. Excess alcohol consumption: 30g/day for males, 20g/day for females 5. Type 1 diabetes mellitus 6. HbA1c>9% 7. Has severe complication of diabetes 8. BMI<20 9. eGFR<45mL/min/1.73m2 10. Dialysis 11. Severe hepatic dysfunction and cirrhosis 12. Females who have a possibility of pregnancy or is pregnant 13. Has malignant neoplasm 14. After surgery and severe trauma 15. History of myocardinal infarction and angina pectoris 16. Had cerebral stroke, cerebral infanction, urinary infection or genital infection within 12 weeks before giving their consent 17. Using steroid and imunosuppressant 18. Using glimepiride>2mg/day, glibenclamide>1.25mg/day, gliclazide>40mg/day 19. Started other diabetic medicines or changed dose within 8 weeks before giving their consent 20. Using GLP-1 receptor agonist or SGLT2 inhibitors 21. In addition, when principal inverstigator or reseacher deems inappriate as a study subject

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
ALT
Secondary Outcome Measures
NameTimeMethod
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