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Comparing efficiency of inhaled Nitrous oxide with intramuscular Pethidine for pain relief during active phase of labor; A Randomized Controlled Trial

Phase 4
Completed
Conditions
labour pain
Registration Number
TCTR20210315002
Lead Sponsor
Vajira Hospital, Navamindrahiraj University
Brief Summary

An inhaled mixture of N2O and oxygen provides pain relief during the active phase of labor compared to intramuscular pethidine,

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Female
Target Recruitment
112
Inclusion Criteria

Nulliparous
age >/=18 years old
GA >/= 37 week
vaginal delivery planning
active phase of first stage of labor
(4 cm 80% + regular contraction)
no drug allergy of entonox and pethidine
requesting pain control

Exclusion Criteria

disable
pulmonary disease
SpO2 < 95 %
B12 or methionone deficiency
history of pneumothorax
pneumocephalus
air embolus
increase intracranial pressure

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
pain score 30/60/90/120 minutes visual analog score
Secondary Outcome Measures
NameTimeMethod
neonatal outcome at min 1/5/10 APGAR score
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