Cognitive, Emotional and Behavioural Impairments in Patients After Sars-Cov2 Infection

Completed

• Conditions: Sars-CoV-2 Infection; COVID-19

• Registration Number: NCT05143320
• Lead Sponsor: Ospedale Generale Di Zona Moriggia-Pelascini

Brief Summary

Recent studies suggest cognitive, emotional and behavioural impairments occur in patients after SARS-CoV-2 infection. Problems with memory, attention, information processing and executive functions are particularly prevalent in these patients, probably due to hypothesised sensitivity of the hippocampus to the virus. Cognitive impairment is also present in patients with no neurological, neuropsychological and neuropsychiatric history. Therefore, the aim of the present study is to describe neuropsychological and neuropsychiatric features in patients recovered from moderate to severe forms of Covid-19 some weeks after hospital dismission.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-08
• Primary Completion: 2021-05-21
• Study Completion: 2021-10-29
• Status Verified: 2021-12
• Study First Submitted: 2021-12-02
• Study First Submitted QC: 2021-12-02
• Last Update Submitted: 2021-12-02
• Study First Posted: 2021-12-03
• Last Update Posted: 2021-12-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 29

Inclusion Criteria

• Positive PCR from nasopharyngeal swab
• No ICU admission

Exclusion Criteria

• Diagnosis of neurologic or psychiatric disorders;
• Previous cognitive impairment;
• Other medical conditions negatively affecting the cognitive status.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive and neuropsychiatirc symptoms in Covid-19 patients	About 20 days after hospital dismission	Prevalence of neuropsychological and neuropsychiatric impairment in patients after hospitalization in patients with Sars-Cov2 infection.

Trial Locations

Locations (1)

"Moriggia Pelascini" Hospital; 🇮🇹 Gravedona, Como, Italy