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Clinical Trials/NCT02322307
NCT02322307
Completed
Not Applicable

A Pragmatic Randomized Controlled Trial to Evaluate the Impact of HealthPROMISE Platform on Quality of Care and Quality of Life in Patients With Inflammatory Bowel Disease

Icahn School of Medicine at Mount Sinai1 site in 1 country320 target enrollmentFebruary 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Inflammatory Bowel Disease
Sponsor
Icahn School of Medicine at Mount Sinai
Enrollment
320
Locations
1
Primary Endpoint
Improvement in Quality Indicators (adapted from the American Gastroenterological Association (AGA) outpatient IBD quality metrics and other consensus recommendations)
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

HealthPROMISE is a mobile application (app) for patients that allows regular tracking of symptoms by patients and communicates them to physicians. The purpose of this randomized controlled trial is to determine the impact of the HealthPROMISE application on improving patient outcomes. The trial will look at how much patients use the application, whether physicians change treatment in response to new information from patients, and how the patients quality of life change over the span of the study. The investigators hypothesize that HealthPROMISE will enhance physician-patient communication and improve clinical outcomes.

Detailed Description

This study will prospectively enroll about 300 patients with Crohn's Disease or Ulcerative Colitis presenting at the Mount Sinai Health System. Eligible participants who complete the informed consent will fill a Tablet or Web-based questionnaire at the end of which they will be given a pin and offered to download the HealthPROMISE app or an education app. Patients who download HealthPROMISE app will then be requested to provide updates on quality metrics, a quality of life questionnaire, and emergency visits and hospitalizations. Data will be collected continuously throughout the study using the mobile health app. Study endpoints will primarily be assessed using "intention to treat" analysis. Additionally, per protocol analysis of data will be performed for patients who have logged into the application at least 4 times in 12 months. The total study duration will be 2 years (104 weeks). At 1 year (52 weeks), an interim analysis will be done to determine if study needs to be continued for full 104 weeks. Furthermore, patients in either arm who login using PIN but not completing week 52 (or week 104) exit survey will be considered as "lost to follow up".

Registry
clinicaltrials.gov
Start Date
February 2015
End Date
January 20, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age \>18 years,
  • Internet or Smartphone access
  • Ability to complete a Tablet or web-based questionnaire in English language.

Exclusion Criteria

  • Presence of short bowel syndrome, stoma or pouch.
  • Presence of a condition or disease that, in the opinion of the investigators, may make it exceedingly difficult for the patient to use HealthPROMISE App, including, but not limited to, advanced dementia.

Outcomes

Primary Outcomes

Improvement in Quality Indicators (adapted from the American Gastroenterological Association (AGA) outpatient IBD quality metrics and other consensus recommendations)

Time Frame: up to 2 years

Quality metrics for primary end-point will be adapted from the American Gastroenterological Association (AGA) outpatient IBD quality metrics and other consensus recommendations.

Secondary Outcomes

  • Short Inflammatory Bowel Disease Questionnaire (SIBDQ)(up to 2 years)
  • Emergency visits and hospitalizations(up to 2 years)
  • Predictors of HealthPromise app utilization (Utilization will be measured through individual logins and data entry in HealthPROMISE app)(up to 2 years)
  • Change in generic QOL score (EQ5D)(at year 1 and at year 2)

Study Sites (1)

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