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Clinical Trials/NCT06363565
NCT06363565
Recruiting
Not Applicable

Study on the Effect of Compound Nutrients on Reducing Homocysteine -- A 3-month Double-blind Randomized Controlled Trial

Sun Yat-sen University1 site in 1 country220 target enrollmentJune 1, 2023
ConditionsHomocysteine

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Homocysteine
Sponsor
Sun Yat-sen University
Enrollment
220
Locations
1
Primary Endpoint
levels of homocysteine
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

The purpose of this study is to determine whether supplementation of compound nutrients, including folic acid, vitamin B6, vitamin B12, and betaine, will decrease the level of plasma homocysteine in Chinese adults with homocysteine levels above 10 μmol/L.

Registry
clinicaltrials.gov
Start Date
June 1, 2023
End Date
December 31, 2025
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Sun Yat-sen University
Responsible Party
Principal Investigator
Principal Investigator

Huilian Zhu

Sun Yat-sen University

Sun Yat-sen University

Eligibility Criteria

Inclusion Criteria

  • Aged 18 - 65 years;
  • Concentration of plasma homocysteine is between 10 and 100 μmol/L;
  • Free from any supplements or drugs that may decrease plasma homocysteine concentration for at least 1 month prior to the beginning of study;
  • Willing to participate in the study and sign informed consent.

Exclusion Criteria

  • Pregnant or lactating women;
  • Allergic physique or allergic to our compound nutrients tablets;
  • Complicated with severe diseases;
  • Unable to conduct study procedures;
  • Participating in any other intervention studies.

Outcomes

Primary Outcomes

levels of homocysteine

Time Frame: 12 weeks

At baseline, 4 weeks, and 12 weeks, blood samples will be drawn and levels of homocysteine will be determined in the two groups.

Study Sites (1)

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