ISRCTN98608690
已完成
不适用
The effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute stroke: a phase II double-blind randomised placebo-controlled trial
Erasmus Medical Center (The Netherlands)0 个研究点目标入组 75 人2002年2月15日
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Stroke
- 发起方
- Erasmus Medical Center (The Netherlands)
- 入组人数
- 75
- 状态
- 已完成
- 最后更新
- 11年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •1\. An acute ischaemic anterior circulation stroke
- •2\. A body temperature greater than 36\.0°C or less than 39\.0°C
- •3\. A CT scan that is compatible with acute ischaemic stroke
- •4\. A focal deficit without rapid improvement
- •5\. A possibility to start treatment within 24 hours after stroke onset
排除标准
- •1\. Severe aphasia, defined as an aphasia score of 2 or 3 on the National Institutes of Health Stroke Scale (NIHSS)
- •2\. Treatment with an non\-Steroidal Anti\-Inflammatory Drug (NSAID) deemed necessary
- •3\. Hypersensitivity to ibuprofen or paracetamol
- •4\. (Chronic) liver failure or cirrhosis
- •5\. (Chronic) renal failure
- •6\. History of alcohol abuse
- •7\. Active gastric ulcer disease or a history of peptic ulceration or gastro\-intestinal haemorrhage in the preceding year
- •8\. Colitis ulcerosa
- •9\. Pregnancy
- •10\. Use of corticosteroids
结局指标
主要结局
未指定
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