Effect of Collagen Peptides, in Combination With Resistance Training, on Body Composition and Muscle Strength in Untrained Men
- Conditions
- Body CompositionMuscle StrengthLean Body MassMuscle Power
- Interventions
- Dietary Supplement: Effect of collagen peptides, in combination with resistance training, on body composition and muscle strength compared to placebo in untrained men
- Registration Number
- NCT06061315
- Lead Sponsor
- University of Southern Denmark
- Brief Summary
The effect of resistance training with post-exercise Collagen peptides (CP) supplementation on lean body mass, maximal and explosive, isometric muscle strength as well as fat mass, resting metabolism, health parameters and compared to resistance training alone will be evaluated in a group of untrained overweight male (30-60 yrs) population in a randomized controlled trial (RCT).
- Detailed Description
Participants will perform supervised resistance training involving (Leg press, pull down, chest press, back extension and abdominal crunches) 3 times a week for 12 weeks. Participants will consume either placebo or collagen peptides (in a double blinded study design) just following resistance training on training days (And approximately the same time of day on non-training days). Prior to, and following 12 weeks of exercise, participants will be tested in body composition, maximal and explosive, isometric muscle strength, resting metabolism, health parameters. Additionally, blood samples will be taken to ensure health and training eligibility and safety.
Participants are healthy untrained overweight males (30-60 yrs)
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 80
- Male, between 30 and 60 years of age
- Fat mass >25 % as measured by bioelectrical impedance analysis
- Stable weight (±5 %) and eating behaviour within the last 3 months.
- Signed informed consent
- Regular physical activity >60 min / week
- Stabile or progressive diseases/conditions (including medication) contraindicating or disabling participation in intensive exercise training and/or with potential to affect training adaptation beyond normal variation. For example:
- Contraindications against physical stress corresponding guidelines of American College of Sports Medicine (ACSM)
- Subjective symptoms during exercise (e.g., unusual physical exhaustion, dyspnoea, nausea)
- Moderate to severe mobility limitation (i.e., due to rheumatic disease)
- Diagnosis of cancer within the last 5 years
- Diabetes mellitus I and II uncontrolled arterial hypertension (systolic blood pressure >155 for mmHg and/or diastolic blood pressure >94 mm Hg; mild hypertension under resting condition will be allowed but such participants will be recommended to consult their general practitioner).
- Conditions contraindicating the supplementation protocol.
- Contraindications against nutritional or ergogenic supplements
- Allergy/aversion against animal protein
- Liver or kidney diseases with a non-permission to ingest certain concentrations of protein.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Collagen peptide group Effect of collagen peptides, in combination with resistance training, on body composition and muscle strength compared to placebo in untrained men This group will consume 1 serving of Collagen peptides, which is produced and marketed ® by GELITA AG, Germany under the brand name BODYBALANC each day.
- Primary Outcome Measures
Name Time Method Lean body mass (kg) Pre (1week prior to intervention) and post (1 week following intervention. i.e 14weeks after inclusion) intervention - about 20 minutes for all dxa-measurements Lean body mass measured by dual-energy X-ray absorptiometry (DXA)
- Secondary Outcome Measures
Name Time Method Resting energy expenditure (kcal pr. day) Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - 15-25 minutes for all dxa-measurements Resting energy expenditure measured with the ventilated hood and indirect calorimetry
1 Repetition maximum strength (kg) Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 25 minutes for all 1RM measurements 1 repetition maximum strength in leg press, pull down and chest press
Maximal isometric knee extensor force (Nm) Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 25 minutes for all isokinetic dynamometer measurements Maximal isometric knee extensor force
Fat mass (kg) Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 20 minutes for all dxa-measurements Fat mass measured by dual-energy X-ray absorptiometry (DXA)
Knee extensor power (W) Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 15 minutes Unilateral knee extensor power (W)
Sit to stand Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 3 minutes 30 second sit to stand test
Rate of force development (Nm/sec) Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 25 minutes for all isokinetic dynamometer measurements Unilateral rate of force development from onset of force until 0-30, 0-50, 0-100, 0-200ms of the knee extensor
Full body bone mineral density (g/cm^2) Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 20 minutes for all dxa-measurements Full body bone mineral density (BMD) (obtained by DEXA)
Trial Locations
- Locations (1)
The Department of Sports Science and Clinical Biomechanics at University of Southern Denmark
🇩🇰Odense, Denmark