Effect of Collagen Peptides, in Combination With Resistance Training, on Body Composition and Muscle Strength in Untrained Men
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Lean body mass (kg)
研究概览
简要总结
The effect of resistance training with post-exercise Collagen peptides (CP) supplementation on lean body mass, maximal and explosive, isometric muscle strength as well as fat mass, resting metabolism, health parameters and compared to resistance training alone will be evaluated in a group of untrained overweight male (30-60 yrs) population in a randomized controlled trial (RCT).
详细描述
Participants will perform supervised resistance training involving (Leg press, pull down, chest press, back extension and abdominal crunches) 3 times a week for 12 weeks. Participants will consume either placebo or collagen peptides (in a double blinded study design) just following resistance training on training days (And approximately the same time of day on non-training days). Prior to, and following 12 weeks of exercise, participants will be tested in body composition, maximal and explosive, isometric muscle strength, resting metabolism, health parameters. Additionally, blood samples will be taken to ensure health and training eligibility and safety.
Participants are healthy untrained overweight males (30-60 yrs)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Investigator)
盲法说明
Participants will be allocated to either placebo or collagen peptide supplementation in a double blinded randomized design.
Only following completion of all participants will the blinding be removed
入排标准
- 年龄范围
- 30 Years 至 60 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Male, between 30 and 60 years of age
- •Fat mass >25 % as measured by bioelectrical impedance analysis
- •Stable weight (±5 %) and eating behaviour within the last 3 months.
- •Signed informed consent
排除标准
- •Regular physical activity >60 min / week
- •Stabile or progressive diseases/conditions (including medication) contraindicating or disabling participation in intensive exercise training and/or with potential to affect training adaptation beyond normal variation. For example:
- •Contraindications against physical stress corresponding guidelines of American College of Sports Medicine (ACSM)
- •Subjective symptoms during exercise (e.g., unusual physical exhaustion, dyspnoea, nausea)
- •Moderate to severe mobility limitation (i.e., due to rheumatic disease)
- •Diagnosis of cancer within the last 5 years
- •Diabetes mellitus I and II uncontrolled arterial hypertension (systolic blood pressure >155 for mmHg and/or diastolic blood pressure >94 mm Hg; mild hypertension under resting condition will be allowed but such participants will be recommended to consult their general practitioner).
- •Conditions contraindicating the supplementation protocol.
- •Contraindications against nutritional or ergogenic supplements
- •Allergy/aversion against animal protein
- •Liver or kidney diseases with a non-permission to ingest certain concentrations of protein.
研究组 & 干预措施
Collagen peptide group
This group will consume 1 serving of Collagen peptides, which is produced and marketed ® by GELITA AG, Germany under the brand name BODYBALANC each day.
干预措施: Effect of collagen peptides, in combination with resistance training, on body composition and muscle strength compared to placebo in untrained men (Dietary Supplement)
Placebo group
This group will consume 1 serving of silicon dioxide (Sipernat 350, Evonik, Germany) each day. The product is absorbed in negligible amounts by the intestine and does therefore induce minor metabolic effects.
干预措施: Placebo Control intervention: Effect of resistance training in combination with placebo (silicon dioxide), on body composition and muscle strength in untrained men (Dietary Supplement)
结局指标
主要结局
Lean body mass (kg)
时间窗: Pre (1week prior to intervention) and post (1 week following intervention. i.e 14weeks after inclusion) intervention - about 20 minutes for all dxa-measurements
Lean body mass measured by dual-energy X-ray absorptiometry (DXA)
次要结局
- 1 Repetition maximum strength (kg)(Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 25 minutes for all 1RM measurements)
- Maximal isometric knee extensor force (Nm)(Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 25 minutes for all isokinetic dynamometer measurements)
- Fat mass (kg)(Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 20 minutes for all dxa-measurements)
- Knee extensor power (W)(Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 15 minutes)
- Sit to stand(Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 3 minutes)
- Rate of force development (Nm/sec)(Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 25 minutes for all isokinetic dynamometer measurements)
- Full body bone mineral density (g/cm^2)(Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - about 20 minutes for all dxa-measurements)
- Resting energy expenditure (kcal pr. day)(Pre (1 week prior to intervention) and post (1 week following intervention. i.e 14 weeks after inclusion) intervention - 15-25 minutes in total)
- Blood sampling(Pre (1week prior to intervention) and post (1 week following intervention. i.e 14weeks after inclusion) intervention - about 3 minutes)