Feedbacks' Influence on Decision Making Processes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 76
- 试验地点
- 2
- 主要终点
- Behavioral performance (Reaction times)
研究概览
简要总结
The purpose of this research is to identify and probe the neural networks involved in feedback processing. It aims at translating this knowledge to clinical populations in which this network is disrupted or compromised.
It includes two studies: 1) with fMRI in healthy subjects to identify the neural bases of feedback processing on decision making using different types of feedback (neutral, social and monetary) presented either infra- or supra-laminary and 2) probing the role of one structure, the anterior cingulate cortex, using Galvanic Vestibular Stimulation (GVS) in healthy subjects. The interventional part consists in the administration of Galvanic Vestibular Stimulation (GVS), which by means of small intensity currents activates the vestibular organs and subsequently vestibular-related brain areas. GVS will be delivered to healthy participants engaged in behavioural tasks requiring the processing of feedbacks of different nature (e.g. social or monetary feedbacks)
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Benefit of social health security
- •Normal or corrected-to-normal vision
排除标准
- •Anamnesis of neurological of psychiatric illness
- •Pregnancy or breastfeeding
- •Administrative measures restricting legal rights
- •Epilepsy (including familiarity), migraines, chronic headaches
- •presence of pacemakers, cochlear implants, surgical clips, or any metallic component fixed in participants' body
- •Current treatment with psychotropic drugs
- •Alcohol assumption during the last 24 hours
- •Sleep deprivation
- •Recent participation to other brain stimulation studies (< 1 week)
研究组 & 干预措施
healthy volunteers
干预措施: mRI (Other)
healthy volunteers
干预措施: Effect of Galvanic Vestibular Stimulation on decision making processes (Other)
结局指标
主要结局
Behavioral performance (Reaction times)
时间窗: up to 4 days
The proportion of reaction times provided, automatically computed by professional programs (e.g. Presentation) running on standard Personal Computers depending on different contexts (e.g. different feedback: neutral, social and monetary).
Behavioral performance (Accuracy)
时间窗: up to 4 days
The proportion of correct responses, automatically computed by professional programs (e.g. Presentation) running on standard Personal Computers depending on different contexts (e.g. different feedback: neutral, social and monetary).
次要结局
- Neural activity (BOLD signal measured using fMRI) as a function of the nature of the feedback.(up to 4 days)