Add On Effect Of Marma Therapy Along With Murivenna Oil Local Application In Sprain

Phase 2/3

Not yet recruiting

• Conditions: Other specified acquired deformities of musculoskeletal system. Ayurveda Condition: SNAYUGATAVATAH,

• Registration Number: CTRI/2025/04/084798
• Lead Sponsor: Majgaonkar Pradnya Tulshidas

Brief Summary

After clearance from the Institutional Ethics Committee Government Ayurveda College and Hospital, Nagpur, screening of Population will be done from OPD, IPD and Casualty of our institute, 90 patients of Sprain will be included. If patients fulfill the criteria of inclusion, subject would also be given freedom to ask their questions and all questions would be answered. If he/she agrees for participation in study and found fit to include; the patient will be included in the study.

Study design: Open Label Randomised Controlled Trial



Study setting: The patients attending OPD and IPD of Shalyatantra Department of our Institute will be selected as subjects for this research study.



Study population: Patients attending OPD and IPD of Shalyatantra Department having signs and symptoms of "Snayugata Vata" will be selected.



Duration of study: 18 months after approval of synopsis



Duration of Treatment: 7 days



Sample Size



1) % Efficacy of Murivenna Taila = 50%



2) % Efficacy of Marma chikista with Murivenna Taila = 53%



3) Power (1 - beta)% = 80%



4) Alpha error %= 5%



Required sample size per group is 42.



Considering 10% dropout/ non-cooperative patients, final sample size is 45 per group.



MATCHING CRITERIA



A. Patients having age between 18-60 years.



B. Patients having clinical signs and symptoms of Snayugata Vata i.e. Sprain - Sandhishoola, Sandhishotha, Sandhi pidanasahatva and Hanti Sandhigotah.



DIAGNOSTIC CRITERIA



Clinical diagnosis will be done by assessing the presenting signs and symptoms:



Sandhishoola - Pain in the joint



Sandhishotha - Swelling over the joint



Sandhi pidanasahatva - Tenderness in the joint



Hanti sandhigatoh - Restricted movements of joint



Methods of Measurement:



Subjective Parameters



A) Local Pain (Shoola) Visual Analogue Scale (VAS) for pain



B) Restricted Movements of Joints ( Hanti sandhigatoh)



Objective Parameters



A) Local tenderness ( Sandhi pidanasahatva)



B) Local swelling ( Sandhishotha)



Clinical Investigations:



1.Complete Blood Count with Erythrocyte Sedimentation Rate



3.Blood Sugar Level: Fasting, Postprandial



Radiological Investigations:



X-ray of the affected joint (Left or Right) : ANTERO- POSTERIOR AND LATERAL VIEW



GROUP A: TRIAL GROUP - Marma Chikitsa along with Murivenna Taila application once a day for 7 days



GROUP B: CONTROL GROUP - Murivenna Taila application once a day for 7 Days

Detailed Description

Not available

Study Timeline

• Study Start: 2025-04-24
• Last Update Posted: 2025-12-04

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Patients willing to participate in the study.
• Patients of age group 18-60 years will be selected.
• Patients will be randomly selected irrespective of sex, marital status, religion, educational status.
• Patients with Pratyatmalakshana of Snayugata vata i.e. pain in the joint (Sandhishoola), swelling (Sandhishotha), tenderness (Sandhi pidanasahatva) and restricted movements of joint (Hanti Sandhigatoh).
• Patients having traumatic history but not associated with fracture, dislocation and ligamental tear associated with Grade 2 and 3 sprain.
• Patients suffering from Snayugata Vata (Grade 1 sprain) without any major illness.
• Patients suffering from only upper or lower extremities joint sprain.
• Co-operative patients.
• Patients with controlled Diabetes Mellitus and blood pressure.

Exclusion Criteria

• Patients not willing to participate in the study.
• Patients of joint dislocation/ fracture or having the history of same.
• Patients with Grade 2 and Grade 3 joint sprain.
• Patients having previous history of ligament or bony reconstructive surgery to affected joint.
• Patients presenting with wound over joint along with sprain.
• Patients with congenital deformities of particular joint.
• Immuno-compromised patients.
• Non co-operative patients.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1) To study the effect of Marma chikitsa along with Murivenna taila application in the management of Snayugata Vata with special reference to Sprain.	Follow up on 8th day, 15th day
2) To study the effect of Murivenna taila application in the management of Snayugata Vata with special reference to Sprain.	Follow up on 8th day, 15th day
3) To compare the effect of Murivenna taila application and add on effect of Marma Chikitsa along with Murivenna taila application in the management of Snayugata Vata with special reference to Sprain.	Follow up on 8th day, 15th day

Secondary Outcome Measures

Name	Time	Method
To study the literature regarding Therapy and Disease through the Ayurvedic Texts and Modern Medical Science.	Follow up on 8th day, 15th day

Trial Locations

Locations (1)

Government Ayurved College and Hospital; 🇮🇳 Nagpur, MAHARASHTRA, India

Government Ayurved College and Hospital

🇮🇳Nagpur, MAHARASHTRA, India

Dr Pradnya Tulshidas Majgaonkar

Principal investigator

9820148691

pradnya.majgaonkar99@gmail.com