NL-OMON44987已完成不适用
[11C]Erlotinib tumor heterogeneity: an in vivo study using static whole body positron emission tomography in non-small cell lung cancer patients. - [11C]erlotinib tumor heterogeneity in WB PET in patients with NSCLC
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Three groups of 10 evaluable patients, i.e. 30 evaluable patients, with histologically proven NSCLC, with an activating EGFR mutation as assessed by HRM and DNA-sequencing;- Three groups are:;1. Patients who were never treated with TKI, planned to receive TKI therapy. ;2. Patients who relapse under TKI therapy, planned to stop TKI therapy;3. Patients who relapsed after second line cytotoxic chemotherapy and are planned for TKI retreatment. ;- Age between 18 and 70 years;- Life expectancy of at least 12 weeks;- Malignant lesions (at least 2) of at least 1.5 cm diameter as measured by CT ;- Karnofsky index ><=60%;- Written informed consent
排除标准
- •- Claustrophobia;- Pregnant or lactating patients;- Concurrent treatment with experimental drugs
研究者
相似试验
已完成
不适用
[11C]Erlotinib pharmacokinetics: an in vivo study using positron emission tomography in non-small cell lung cancer patients with and without erlotinib therapy.non-small cell lung carcinoma10038666lung cancerNL-OMON36826Vrije Universiteit Medisch Centrum10
尚未招募
不适用
[11C]Erlotinib in non-small cell lung cancer patients with and without erlotinib therapy.on-small cell lung cancer NSCLCNiet-kleincellig longkankerNL-OMON28948VU University Medical Center10
已完成
2 期
Erlotinib in Treating Patients With Locally Advanced or Metastatic Stomach Cancer or Gastroesophageal Junction CancerGastric CancerEsophageal CancerNCT00032123SWOG Cancer Research Network
招募中
不适用
In-vivo Bioequivalence Test of Erlotinib tablets with brand drug (TARCEVA® 150 mg, Rosche, Switzerland)IRCT20200105046010N46Actero Pharma. Co.24
已完成
1 期
Phase I Imaging Study Evaluating Dalotuzumab (MK0646) in Combination With Erlotinib for Patients With Non-Small Cell Lung Cancer (MK-0646-008)Carcinoma, Non-small Cell LungNCT00729742Merck Sharp & Dohme LLC49