Cerebral Microembolism in Interventional Cardiology Procedures
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cerebral Embolism
- Sponsor
- Insel Gruppe AG, University Hospital Bern
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- Quality of cerebral microemboli (solid vs. gaseous)
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
During different interventional cardiology procedures we aim to identify cerebral microemboli load. Further we aim to differentiate the quality and the quantity of cerebral microemboli.We will measure cerebral microemboli in different interventional phases, e.g. during valve deployment, rapid pacing, post-implantation.
Investigators
Gabor Erdös
Principal Investigator
Insel Gruppe AG, University Hospital Bern
Eligibility Criteria
Inclusion Criteria
- •Age \> 18 years
- •Interventional cardiology procedure (TAVI, MitraClip, TricuspidalClip)
Exclusion Criteria
- •Allergy to ultrasound gel or materials contained in the TCD probe
- •Missing temporal bone window
Outcomes
Primary Outcomes
Quality of cerebral microemboli (solid vs. gaseous)
Time Frame: intraoperative phase, expected to be approx. 4 hours
The quality of cerebral microemboli is measured by Doppler ultrasonography which automatically detects and analyses the Doppler signal coming from the middle cerebral artery. According to the strength of signal reflection, the signal will be qualified as solid or gaseous.
Secondary Outcomes
- Quantity of cerebral microemboli load(intraoperative phase, expected to be approx. 4 hours)
- Cerebral hemispheric differences (left vs. right)(intraoperative phase, expected to be approx. 4 hours)