Effect of 12-week Fitness Walking Programme on Sex Hormone Levels and Risk Factors for Metabolic Syndrome in Postmenopausal Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Fasting blood glucose (FBG)
研究概览
简要总结
Postmenopausal women were separated into two groups: one participating in a 12-week fitness walking programe as the fitness walking group, and the other maintaining their regular lifestyle as the control group. The study evaluated alterations in health markers and examined the correlation between metabolic syndrome risk factors and sex hormone levels before and after the intervention.
详细描述
According to the inclusion and exclusion criteria, our study invlved postmenopausal women aged from 50 to 69 years old. After the selection process, baseline assessments were conducted, including evaluations of metabolic syndrome risk factors, body morphology measurements, sex hormone levels, and cardiopulmonary exercise testing. Participants were then randomly assigned to either the fitness walking group or the control group using a random number table. Participants in the fitness walking group completed a 12-week fitness walking program, while those in the control group maintained their usual lifestyle without any intervention. During the post-intervention assessment, all baseline measurements were repeated to evaluate changes in the previously measured indicators.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 69 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •(1) Participants were entirely voluntary and capable of completing the full 12-week intervention process.
- •(2) Participants were postmenopausal women aged between 50 and 69 years.
- •(3) Participants had been postmenopausal for over 12 months and had not received exogenous estrogen supplementation post-menopause.
排除标准
- •(1) Participants had a history of acute or chronic musculoskeletal disorders, cardiovascular diseases, diabetes, or other conditions that might impact their ability to engage in the intervention.
- •(2) Participants had recent hormone treatment, anti-inflammatory medication use, or other medications affecting blood indices.
- •(3) Participants experienced unstable body weight (fluctuations exceeding 2.5 kg) in the past three months.
- •(4) Participants were concurrently enrolled in other intervention studies or maintained regular exercise routines.
- •(5) Participants had smoking or alcohol consumption habits.
研究组 & 干预措施
Fitness walking group
干预措施: Fitness walking (Behavioral)
Control group
干预措施: Maintained lifestyle (Behavioral)
结局指标
主要结局
Fasting blood glucose (FBG)
时间窗: At the beginning-at 12 weeks.
The change of FBG before and after intervention
Waist circumference (WC)
时间窗: At the beginning-at 12 weeks.
The change of WC before and after intervention
Diastolic blood pressure (DBP)
时间窗: At the beginning-at 12 weeks.
The change of DBP before and after intervention
High-density lipoprotein cholesterol (HDL-C)
时间窗: At the beginning-at 12 weeks.
The change of HDL-C before and after intervention
Systolic blood pressure (SBP)
时间窗: At the beginning-at 12 weeks.
The change of SBP before and after intervention
Triglycerides (TG)
时间窗: At the beginning-at 12 weeks.
The change of TG before and after intervention
次要结局
- Oestradiol (E2)(At the beginning-at 12 weeks.)
- Dehydroepiandrosterone sulphate (DHEA-S)(At the beginning-at 12 weeks.)
- Testosterone (T)(At the beginning-at 12 weeks.)
- Sex hormone-binding globulin (SHBG)(At the beginning-at 12 weeks.)
- Body weight (BW)(At the beginning-at 12 weeks.)
- Maximal oxygen uptake (VO2max)(At the beginning-at 12 weeks.)
- Height(At the beginning-at 12 weeks.)
- Body mass index (BMI)(At the beginning-at 12 weeks.)