Acute Neurocardiogenic Injury After Subarachnoid Hemorrhage.

Completed

• Conditions: Subarachnoid Hemorrhage

• Registration Number: NCT01218191
• Lead Sponsor: Direction Centrale du Service de Santé des Armées

Brief Summary

The aim of this study is to describe acute neurocardiogenic injury after subarachnoid hemorrhage assessed with cardiac 123I-MIBG scintigraphy and 18F-FDG PET/CT during the first week and the first six months after SAH.

The study hypothesis is that the evolution of the cardiac disturbances follows the clinical evolution.

Detailed Description

The cardiac metabolic disturbance are assessed by a 18F-FDG PET/CT in the first week after SAH and monthly until normal result.

The myocardial sympathetic innervation is assessed by a cardiac 123I-MIBG scintigraphy in the first week after SAH and six months later.

Clinical outcome is assessed by Glasgow Outcome Scale, modified Rankin Scale and MOS-SF36 at 1, 3 and 6 months after SAH.

Study Timeline

• Study Start: 2010-02
• Study First Submitted: 2010-10-06
• Study First Submitted QC: 2010-10-08
• Study First Posted: 2010-10-11
• Status Verified: 2012-02
• Primary Completion: 2012-02
• Study Completion: 2012-02
• Last Update Submitted: 2012-02-17
• Last Update Posted: 2012-02-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• age
• SAH
• Hospitalization in the Military Teaching Hospital Sainte Anne

Exclusion Criteria

• Refusal of consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cardiac 18F-FDG PET	first week after SAH

Secondary Outcome Measures

Name	Time	Method
cardiac 18F-FDG PET	one month after first cardiac 18F-FDG PET
cardiac 123I-MIBG scintigraphy	Six months after SAH

Trial Locations

Locations (1)

Intensive Care Unit, Military Teaching Hospital sainte Anne; 🇫🇷 Toulon, France