Effects of Physical Activity on Weight Loss and Weight Maintenance in Obese Adults - Three Year Follow-up Study

Not Applicable

Completed

• Conditions: Weight Loss; Obesity; Physical Activity; Healthy Obesity, Metabolically
• Interventions: Behavioral: Lifestyle modification

• Registration Number: NCT03861754
• Lead Sponsor: University of Oulu

Brief Summary

Objective To study if exercise added to weight loss treatment at the beginning of the weight loss intervention or at 6 months could sustain the weight loss achieved or give extra boost for weight reduction.

Design 36-month, 4-group parallel, randomized trial.

Setting Oulu, Finland.

Participants 120 obese adults (body mass index ≥ 30).

Intervention Participants were randomly assigned to behavioural modification (iBM) (n = 30), behavioural modification + exercise from 0 to 3 months (CWT1) (n = 30), behavioural modification + exercise from 6 to 9 months (CWT2) (n = 30), and a control group (CON) (n = 30). Questionnaires and measurements were performed at baseline, 3,9,4 and 36 months. The intervention consisted of an intensified weight loss period (1-12 months) followed by a weight maintenance period (13-36 months). Intensified behavioural modification included 14 individual face to face meetings, eleven times with a personal therapist (qualified nurse) and three times with a nutritionist. Weight maintenance period included six individual meetings with personal therapist. Twelve weeks supervised exercise was offered three times a week, 40 minutes at a time. In the CWT1 group supervised exercise was offered at months 1-3 and in the CWT2 group at months 4-6.

Measurements Body weight (primary outcome) and waist circumference (secondary outcome)

Detailed Description

Not available

Study Timeline

• Study Start: 2004-01-28
• Primary Completion: 2010-05
• Study Completion: 2010-05
• Status Verified: 2019-02
• Study First Submitted: 2019-02-26
• Study First Submitted QC: 2019-02-28
• Last Update Submitted: 2019-02-28
• Study First Posted: 2019-03-04
• Last Update Posted: 2019-03-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Body mass Index > 30
• Age 18-64

Exclusion Criteria

• Pregnancy
• Health reasons preventing exercise and exercise test
• Medication preventing exercise and exercise test
• Previously diagnosed diabetes

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Lifestyle modification and exercise 2	Lifestyle modification	Intensified Behavioural Modification and exercise from 6 to 9 months (CWT2) group: Lifestyle counselling 3 months Exercise intervention from 6 to 9 months
Lifestyle modification	Lifestyle modification	intensified Behavioural Modification (iBM) group receiving lifestyle counselling
Lifestyle modification and exercise 1	Lifestyle modification	Intensified Behavioural Modification and exercise from 0 to 3 months (CWT1) group: Lifestyle counselling 3 months Exercise intervention from 0 to 3 months

Primary Outcome Measures

Name	Time	Method
Weight change	Change from baseline weight at 36 months	Kilograms

Secondary Outcome Measures

Name	Time	Method
Waist circumference change	Change from baseline waist circumference at 36 months	Cm

Trial Locations

Locations (1)

Oulu Deaconess Institute Foundation sr; 🇫🇮 Oulu, Finland