A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
- Conditions
- NASH - Nonalcoholic Steatohepatitis
- Interventions
- Drug: IVA337Drug: Placebo
- Registration Number
- NCT04849728
- Lead Sponsor
- Inventiva Pharma
- Brief Summary
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
- Detailed Description
Primary objectives
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis stage F2 or F3 and consists of 2 sequential parts - an initial double-blind placebo-controlled (DBPC) period (Part A) followed by a double-blind active treatment extension (ATE) period (Part B), with the following primary objectives:
Part A To assess the safety and efficacy of lanifibranor compared to placebo on 'NASH resolution and improvement of fibrosis' assessed by liver histology.
Part B To assess the safety of lanifibranor beyond the DBPC period. Secondary objectives
Key secondary objectives of Part 1:
* To assess the effect of lanifibranor compared to placebo on NASH resolution and no worsening of fibrosis
* To assess the effect of lanifibranor compared to placebo on improvement of fibrosis with no worsening of NASH
Other secondary objectives of both Part 1 and Part 2:
* To assess the effect of lanifibranor on other key histological features of NASH (only for DBPC period)
* To assess the effect of lanifibranor on NASH resolution and improvement of fibrosis in diabetic patients (only for DBPC period)
* To assess the effect of lanifibranor on liver tests
* To assess the effect of lanifibranor on glycaemic parameters
* To assess the effect of lanifibranor on lipid parameters
* To assess the effect of lanifibranor on liver stiffness and steatosis assessed by elastography.
* To assess the effect of lanifibranor on health-related quality of life
* To assess the safety of lanifibranor
* To assess population PK modeling through plasma levels of lanifibranor using sparse sampling scheme (only for DBPC period)
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 1000
-
Male or female, aged ≥18 years at the time of signing informed consent
-
Upon central biopsy reading process: diagnosis of NASH according to the Steatosis-Activity-Fibrosis (SAF):
- Steatosis score ≥1
- Activity score: A3 or A4
- Fibrosis score: F2 or F3
-
No qualitative change in dose for the drugs listed below:
- Antidiabetic treatment if glucagon-like peptide-1 receptor agonists (GLP1 receptor agonists) or sodium-glucose co-transporter-2 inhibitors (SGLT2 inhibitors): for at least 3 months
- Vitamin E (if at a dose ≥400 IU/day): for at least 6 months
- Statins: for at least 3 months
-
No qualitative change in dose for all other chronically administered drugs for at least 3 months prior to Screening
-
Weight stable for 6 months prior to Screening and between the qualifying liver biopsy and Baseline (no more than 5% change for both periods)
-
Negative serum pregnancy test at study Screening for females of childbearing potential confirmed by central laboratory. Females of childbearing potential must practice a consistent and proper use of highly effective method of contraception throughout the study and for 1 month after treatment discontinuation.
Liver-related:
-
Documented causes of chronic liver disease other than NASH
-
Histologically documented liver cirrhosis (fibrosis stage F4)
-
History or current diagnosis of hepatocellular carcinoma (HCC)
-
History of or planned liver transplant
-
Positive human immunodeficiency virus (HIV) serology
-
ALT or AST >5 × ULN
-
AST<0.6 ULN if the liver biopsy has to be performed in the scope of the study
-
Abnormal synthetic liver function as defined by Screening central laboratory evaluation
-
Haemoglobin <110 g/L (11 g/dL) for females and <120 g/L (12 g/dL) for males
-
Patient currently receiving any approved treatment for NASH or obesity
-
Current or recent history (<5 years) of significant alcohol consumption
-
Treatment with drugs that may cause non-alcoholic fatty liver disease (NAFLD) administered for at least 2 weeks within 12 months prior to qualifying liver biopsy
Glycaemia related:
-
HbA1c >9% at Screening
-
Diabetes mellitus other than type 2
-
Current treatment with insulin
-
Treatment with PPAR-gamma agonists (thiazolidinediones [TZDs]) 12 months before screening or historical biopsy.
Obesity related:
-
Bariatric surgery: Restrictive procedures are allowed, if performed >6 months prior to the qualifying liver biopsy; malabsorptive procedures and procedures combining both restrictive and malabsorptive methods are not allowed within 5 years of the qualifying liver biopsy.
Cardiovascular related:
-
History of heart failure with reduced left ventricular ejection fraction (LVEF)
-
Atrial fibrillation requiring anticoagulation
-
Unstable heart failure
-
Uncontrolled hypertension at Screening (values >160/100 mm Hg)
General safety:
-
Women currently breastfeeding
-
Previous exposure to lanifibranor
-
Participation in any clinical trial investigational medicinal product/device within 3 months from Screening or 5 half-lives from Screening, whichever is longer
-
Concomitant treatment with PPAR-alpha agonists (fibrates)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Lanifibranor (IVA 337) (800 mg/day) Placebo 2 Lanifibranor tablets 400mg + 1 Placebo to match tablet with food --\> once a day (quaque die, QD) Lanifibranor (IVA 337) (800 mg/day) IVA337 2 Lanifibranor tablets 400mg + 1 Placebo to match tablet with food --\> once a day (quaque die, QD) Matching placebo Placebo 3 Placebo to match tablets with food --\> once a day (quaque die, QD) Lanifibranor (IVA 337) (1200 mg/day) IVA337 3 Lanifibranor tablets 400mg with food --\> once a day (quaque die, QD)
- Primary Outcome Measures
Name Time Method Safety Analyses 48 weeks after completion of DBPC period Part B: ATE:
* Using the DBPC on-treatment period, comparing the 2 active arms versus placebo
* Using the DBPC +ATE on treatment periods, assessing the 2 active arms. For adverse events, adjudicated liver events, and DILI and MACE events, in addition to the raw cumulative incidence proportions, the exposure-adjusted incidence rates will be provided based on the time patients are at risk.Resolution of NASH and improvement of fibrosis Part A: Date of randomisation until the date of biopsy at Week 72 Part A: DBPC: Resolution of NASH and improvement of fibrosis at Week 72, defined by NASH CRN scores for ballooning of 0 and inflammation of 0 to 1, and fibrosis score ≥1 stage decrease compared to Baseline
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (483)
Mercy Medical Center - Mcauley Plaza
🇺🇸Baltimore, Maryland, United States
National Research Institute - Westlake
🇺🇸Los Angeles, California, United States
Fiona Stanley Hospital
🇦🇺Murdoch, Western Australia, Australia
Chevy Chase Clinical Research
🇺🇸Chevy Chase, Maryland, United States
University Hospitals Case Medical Center
🇺🇸Cleveland, Ohio, United States
University of Pittsburgh Medical Center
🇺🇸Pittsburgh, Pennsylvania, United States
Massachusetts General Hospital
🇺🇸Boston, Massachusetts, United States
Life Medical Research Group
🇺🇸Miami, Florida, United States
Liver Associates of Texas
🇺🇸Houston, Texas, United States
Headlands - Centex Studies - Westfield
🇺🇸Houston, Texas, United States
Research and Education, Inc.
🇺🇸San Diego, California, United States
Consultants for Clinical Research - Montgomery Office
🇺🇸Cincinnati, Ohio, United States
Clínica Universidad de Navarra
🇪🇸Madrid, Spain
Hospital Universitario Virgen de Valme
🇪🇸Sevilla, Spain
Synexus Polska Sp. z o.o. Oddzial w Gdansku
🇵🇱Gdańsk, Poland
Beijing You'an Hospital,Capital Medical University
🇨🇳Beijing, Fengtai, China
Nanfang Hospital of Southern Medical University
🇨🇳Guangzhou, Guangdong, China
The Eighth Affiliated Hospital,GuangZhou Medical University
🇨🇳Guangzhou, Guangdong, China
The First Affiliated Hospital Sun Yat-sen University
🇨🇳Guangzhou, Guangdong, China
The First Affiliated Hospital of Guangxi Medical University
🇨🇳Nanning, Guangxi, China
The Affiliated Hospital of Guizhou Medical University
🇨🇳Guiyang, Guizhou, China
Fourth Affiliated Hospital of Harbin Medical University
🇨🇳Harbin, Heilongjiang, China
The First Affiliated Hospital of Henan University of Science and Technology
🇨🇳Luoyang, Henan, China
The First Affiliated Hospital of Nanyang Medical College
🇨🇳Nanyang, Henan, China
Sanmenxia Central Hospital
🇨🇳Sanmenxia, Henan, China
Henan Provincal People's Hospital
🇨🇳Zhengzhou, Henan, China
Jiangsu Provincial People's Hospital
🇨🇳Nanjing, Jiangsu, China
Union Hospital Tongji Medical College Huazhong University of Science and Technology
🇨🇳Wuhan, Hubei, China
The Second Affiliated Hospital of Nanchang University
🇨🇳Nanchang, Jiangxi, China
First Affiliated Hospital of China Medical University
🇨🇳Shenyang, Liaoning, China
The Sixth People' s Hospital Of ShenYang
🇨🇳Shenyang, Liaoning, China
Xi'an International Medical Center
🇨🇳Xi'an, Shaanxi, China
Qingdao Central Hospital
🇨🇳Qingdao, Shandong, China
Xu, Jun The First Hospital of Shanxi Medical University Taiyun Shanxi
🇨🇳Taiyuan, Shanxi, China
The First Affiliated Hospital of Xi'an Jiaotong University
🇨🇳Xi'an, Shanxi, China
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
🇨🇳Chengdu, Sichuan Shi, China
The Second Hospital of Tianjin Medical University
🇨🇳Tianjin, Tianjin, China
The First People's Hospital of Yunnan Province
🇨🇳Kunming, Yunnan, China
The First Affiliated Hospital , Zhejiang University School of Medicine
🇨🇳Hangzhou, Zhejiang, China
RuiAn People's Hospital - Ruixiang Branch
🇨🇳Ruian, Zhejiang, China
The First Affiliated Hospital of Wenzhou Medical University
🇨🇳Wenzhou, Zhejiang, China
Xiangya Hospital - Central South University
🇨🇳Changsha, China
West china hospital Sichuan University
🇨🇳Chengdu, China
Mengchao Hepatobiliary Hospital of FuJian Medical University
🇨🇳Fuzhou, China
Guangdong Provincial people's hospital
🇨🇳Guangzhou, China
The Third Affiliated Hospital, Sun Yat-Sen University
🇨🇳Guangzhou, China
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine - Qingchun Campus
🇨🇳Hangzhou, China
General Hospital of Tianjin Medical University
🇨🇳Heping, China
Ningbo No.2 Hospital (Hwa Mei Hospital)
🇨🇳Ningbo, China
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
🇨🇳Shanghai, China
Qingdao Municipal Hospital
🇨🇳Qingdao, China
Shengjing Hospital of China Medical University
🇨🇳Shenyang, China
The University of Hong Kong-Shenzhen Hospital
🇨🇳Shenzhen, China
The First Affiliated Hospital of Zhengzhou University
🇨🇳Zhengzhou, China
Zhengzhou People's Hospital
🇨🇳Zhengzhou, China
Universitätsklinikum Schleswig-Holstein - Campus Lübeck
🇩🇪Lübeck, Schleswig-Holstein, Germany
Hospital Provincial del Centenario
🇦🇷Rosario, Santa Fe, Argentina
Eastern Health - Australia
🇦🇺Box Hill, Victoria, Australia
Hospital Italiano La Plata
🇦🇷La Plata, Buenos Aires, Argentina
Niepubliczny Zaklad Opieki Zdrowotnej Centrum Badan Klinicznych
🇵🇱Wrocław, Dolnoslaskie, Poland
Synexus - Gdynia
🇵🇱Gdynia, Pomorskie, Poland
MIND Klinika
🇭🇺Budapest, Hungary
Dél-pesti Centrumkórház - Országos Hematológiai és Infektológiai Intézet
🇭🇺Budapest, Hungary
Hospital Universitario Austral
🇦🇷Pilar, Buenos Aires, Argentina
University Health Network
🇨🇦Toronto, Ontario, Canada
Hôpital Rangueil
🇫🇷Toulouse, Occitanie, France
Elisabeth-TweeSteden Ziekenhuis
🇳🇱Tilburg, North Brabant, Netherlands
University Multiprofile Hospital for Active Treatment St. Ivan Rilski
🇧🇬Sofia, Sofia City, Bulgaria
Hospital Italiano de Buenos Aires
🇦🇷Ciudad Autónoma De Buenos Aires, Buenos Aires, Argentina
The Chaim Sheba Medical Center
🇮🇱Ramat Gan, Tel Aviv, Israel
Synexus - Warszawa
🇵🇱Warszawa, Mazowieckie, Poland
Centro De Investigaciones Clínicas Viña Del Mar
🇨🇱Viña Del Mar, Valparaíso, Chile
Hôpital Haut-Lévêque
🇫🇷Pessac, Nouvelle-Aquitaine, France
Synexus - Katowice
🇵🇱Katowice, Slaskie, Poland
Centrum Medyczne Pratia - Katowice
🇵🇱Katowice, Slaskie, Poland
Panthera Biopartners - Glasgow
🇬🇧Glasgow, North Lanarkshire, United Kingdom
Panthera Biopartners - North London
🇬🇧London, England, United Kingdom
Nottingham University Hospitals NHS Trust
🇬🇧Nottingham, England, United Kingdom
Erasmus Medisch Centrum
🇳🇱Rotterdam, Zuid-Holland, Netherlands
Centro Hospitalar de Trás-Os-Montes e Alto-Douro - Hospital de S. Pedro
🇵🇹Vila Real, Portugal
Royal Surrey County Hospital NHS Foundation Trust
🇬🇧Surrey Quays, England, United Kingdom
The Newcastle Upon Tyne Hospitals NHS Foundation Trust
🇬🇧Newcastle Upon Tyne, England, United Kingdom
California Pacific Medical Center Research Institute
🇺🇸San Francisco, California, United States
Quest Clinical Research
🇺🇸San Francisco, California, United States
Henry Ford Health System
🇺🇸Detroit, Michigan, United States
MNGI Digestive Health - Northeast Minneapolis Clinic
🇺🇸Minneapolis, Minnesota, United States
Duke University Medical Center
🇺🇸Durham, North Carolina, United States
Vanderbilt University Medical Center
🇺🇸Nashville, Tennessee, United States
Quality Research - San Antonio
🇺🇸San Antonio, Texas, United States
Texas Liver Institute/American Research Corporation
🇺🇸San Antonio, Texas, United States
University of California San Diego
🇺🇸San Antonio, Texas, United States
Pinnacle Clinical Research - San Antonio
🇺🇸San Antonio, Texas, United States
ARcare Center for Clinical Research
🇺🇸Little Rock, Arkansas, United States
ARcare Center for Clinical Research - Conway
🇺🇸Conway, Arkansas, United States
Del Sol Research Management - Tucson East
🇺🇸Tucson, Arizona, United States
Gastro Florida
🇺🇸Clearwater, Florida, United States
Bridgeport Hospital
🇺🇸Bridgeport, Connecticut, United States
MedBio Trials
🇺🇸Adventura, Florida, United States
Centor for Advanced Gastroenterology - Main Office - Maitland
🇺🇸Maitland, Florida, United States
Synergy Healthcare
🇺🇸Bradenton, Florida, United States
JY Research Institute Inc.
🇺🇸Cutler Bay, Florida, United States
Top Medical Research
🇺🇸Cutler Bay, Florida, United States
Florida Research Institute
🇺🇸Lakewood Ranch, Florida, United States
Galenus Group
🇺🇸Lehigh Acres, Florida, United States
Digestive Healthcare of Georgia
🇺🇸Atlanta, Georgia, United States
University of Chicago
🇺🇸Chicago, Illinois, United States
Pro Live Medical Research
🇺🇸Miami, Florida, United States
Southeast Clinical Research Center
🇺🇸Dalton, Georgia, United States
IACT Health
🇺🇸Columbus, Georgia, United States
NorthShore University HealthSystem
🇺🇸Skokie, Illinois, United States
Athens Gastroenterology Association
🇺🇸Athens, Georgia, United States
Investigative Clinical Research - Annapolis
🇺🇸Annapolis, Maryland, United States
Advanced Research Institute
🇺🇸New Port Richey, Florida, United States
Miami Dade Medical Research Institute
🇺🇸Miami, Florida, United States
Clinical Trials Services Corporation
🇺🇸Miami, Florida, United States
American Research Centers of Florida
🇺🇸Pembroke Pines, Florida, United States
Research and Education Foundation of Atlanta Medical Center
🇺🇸Atlanta, Georgia, United States
Heartland Medical Research
🇺🇸Clive, Iowa, United States
Sensible Healthcare Clinical Research
🇺🇸Ocoee, Florida, United States
Oracle Clinical Research
🇺🇸College Park, Georgia, United States
ASHA Clinical Research - Munster
🇺🇸Hammond, Indiana, United States
Pensacola GI Research Center
🇺🇸Pensacola, Florida, United States
University of Kansas Medical Center Research Institute
🇺🇸Kansas City, Kansas, United States
Regional Infectious Diseases and Infusion Center
🇺🇸LaGrange, Georgia, United States
Tandem Clinical Research GI, LLC
🇺🇸Metairie, Louisiana, United States
Combined Gastro Research LLC
🇺🇸Lafayette, Louisiana, United States
Tandem Clinical Research GI
🇺🇸Houma, Louisiana, United States
Charlotte Gastroenterology and Hepatology - Randolph Road Office
🇺🇸Charlotte, North Carolina, United States
SSM Health Saint Louis University Hospital
🇺🇸Saint Louis, Missouri, United States
Digestive Disease Associates - Catonsville
🇺🇸Catonsville, Maryland, United States
Gastrointestinal Associates & Endoscopy Center - Flowood
🇺🇸Flowood, Mississippi, United States
NECCR Prima Care Research, LLC
🇺🇸Fall River, Massachusetts, United States
Boston Medical Center
🇺🇸Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center - Liver Center
🇺🇸Boston, Massachusetts, United States
Galen Research
🇺🇸Chesterfield, Missouri, United States
Clinical Research Institute of Michigan
🇺🇸Chesterfield, Michigan, United States
Meritus Center for Clinical Research
🇺🇸Hagerstown, Maryland, United States
Sierra Clinical Research - Las Vegas
🇺🇸Las Vegas, Nevada, United States
Icahn School of Medicine at Mount Sinai
🇺🇸New York, New York, United States
Tandem Clinical Research - New York Clinic
🇺🇸New York, New York, United States
State University of New York - University at Buffalo
🇺🇸Buffalo, New York, United States
Cumberland Research Associates
🇺🇸Fayetteville, North Carolina, United States
Aventiv Research - Columbus
🇺🇸Columbus, Ohio, United States
Ohio Gastroenterology Group, Inc. - Olentangy Office
🇺🇸Dublin, Ohio, United States
The Ohio State University
🇺🇸Columbus, Ohio, United States
INTEGRIS Baptist Medical Center
🇺🇸Oklahoma City, Oklahoma, United States
Great Lakes Gastroenterology Research - Mentor
🇺🇸Mentor, Ohio, United States
Carolina Digestive Diseases
🇺🇸Greenville, North Carolina, United States
Digestive Specialists - Dayton
🇺🇸Dayton, Ohio, United States
ObjectiveGI - Northeast GI Research
🇺🇸Concord, North Carolina, United States
North Shore Gastroenterology
🇺🇸Westlake, Ohio, United States
Texas Clinical Research Institute
🇺🇸Arlington, Texas, United States
Gastroenterology Consultants - Ellington
🇺🇸Houston, Texas, United States
Gadolin Research
🇺🇸Beaumont, Texas, United States
South Texas Research Institute - Brownsville
🇺🇸Brownsville, Texas, United States
Velocity Clinical Research - Austin
🇺🇸Cedar Park, Texas, United States
The Liver Institute at Methodist Dallas
🇺🇸Dallas, Texas, United States
Allure Health, Llc
🇺🇸Friendswood, Texas, United States
Summitt - Pinnacle Clinical Research - Georgetown
🇺🇸Georgetown, Texas, United States
Universitair Ziekenhuis Leuven - Campus Gasthuisberg
🇧🇪Leuven, Flemish Brabant, Belgium
Liver Specialists of Texas
🇺🇸Houston, Texas, United States
Algemeen Ziekenhuis Sint-Jan Brugge-Oostende - Campus Sint-Jan
🇧🇪Brugge, West-Vlaanderen, Belgium
Pioneer Research Solutions
🇺🇸Houston, Texas, United States
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto
🇧🇷Ribeirão Preto, São Paulo, Brazil
Alpha Research Institute, LLC
🇺🇸Houston, Texas, United States
Houston Research Institute (HRI)
🇺🇸Houston, Texas, United States
Koncord Research - McAllen LLC
🇺🇸McAllen, Texas, United States
GI Alliance - Lubbock Digestive Disease Associates - Lubbock
🇺🇸Lubbock, Texas, United States
Sun Research Institute
🇺🇸San Antonio, Texas, United States
University of Utah School of Medicine
🇺🇸Salt Lake City, Utah, United States
Sherman Clinical Research
🇺🇸Sherman, Texas, United States
University of Vermont Medical Center
🇺🇸Burlington, Vermont, United States
Impact Research Institute
🇺🇸Waco, Texas, United States
Digestive Health Research of Central Texas
🇺🇸Waco, Texas, United States
University of Virginia Health System
🇺🇸Charlottesville, Virginia, United States
Klinikum Chemnitz
🇩🇪Chemnitz, Sachsen, Germany
Tel Aviv Sourasky Medical Center
🇮🇱Tel Aviv, Gush Dan, Israel
Ospedale Casa Sollievo della Sofferenza
🇮🇹San Giovanni Rotondo, Foggia, Italy
Klinische Forschung Karlsruhe GmbH
🇩🇪Karlsruhe, Baden-Württemberg, Germany
Charité Universitätsmedizin Berlin
🇩🇪Berlin, Germany
Hôpital Saint-Joseph
🇫🇷Marseille, Bouches-du-Rhône, France
CHU Dijon Bourgogne - Hôpital François Mitterrand
🇫🇷Dijon, Cantal, France
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ)
🇲🇽Ciudad de México, Mexico
First Affiliated Hospital of the Army Military Medical University (Southwest Hospital)
🇨🇳Chongqing, Chongging, China
The Second Affiliated Hospital of Chongqing Medical University
🇨🇳Chongqing, China
Second Affiliated Hospital of Dalian Medical University
🇨🇳Dalian, China
St. Josefs-Hospital Wiesbaden
🇩🇪Wiesbaden, Hessen, Germany
Austin Health
🇦🇺Heidelberg, Victoria, Australia
High Tech Medical Kft.
🇭🇺Budapest, Hungary
Eugastro
🇩🇪Leipzig, Sachsen, Germany
Gastroenterology Associates of Northern Virginia
🇺🇸Fairfax, Virginia, United States
Royal Perth Hospital
🇦🇺Perth, Western Australia, Australia
The First Affiliated Hospital of Chongqing Medical University
🇨🇳Chongqing, Chongqing, China
Hôpital Erasme
🇧🇪Bruxelles, Bruxelles Capitale, Belgium
Investigacion Biomedica para el Desarrollo de Farmacos S.A. de C.V.
🇲🇽Mexico City, Mexico
Hospital Universitario "Dr. José Eleuterio González" (Servicio de Endocrinología)
🇲🇽Monterrey, Mexico
Synexus Czech - DRS Prague
🇨🇿Praha, Czechia
Algemeen Ziekenhuis Delta - Campus Rumbeke
🇧🇪Roeselare, West-Vlaanderen, Belgium
University Multiprofile Hospital for Active Treatment and Emergency Medicine N.I. Pirogov
🇧🇬Sofia, Sofia City, Bulgaria
Diagnostic Consultative Center Aleksandrovska
🇧🇬Sofia, Bulgaria
Chongqing university three gorges hospital
🇨🇳Chongqing, Chongging, China
The First Hospital of Lanzhou University
🇨🇳Lanzhou, Gansu, China
St. Joseph's Healthcare Hamilton - Charlton Campus
🇨🇦Hamilton, Ontario, Canada
Beijing Ditan Hospital, Capital Medical University
🇨🇳Beijing, Beijing, China
Bon Secours Liver Institute of Hampton Roads
🇺🇸Newport News, Virginia, United States
Peking University People's Hospital
🇨🇳Beijing, Beijing, China
Hospital das Clinicas da Universidade Federal de Minas Gerais
🇧🇷Belo Horizonte, Minas Gerais, Brazil
Acibadem City Clinic Tokuda Hospital
🇧🇬Sofia, Bulgaria
Diagnostic Consulting Center 20 - Sofia Еооd
🇧🇬Sofia, Bulgaria
Nov Rehabilitatsionen Tsentar EOOD
🇧🇬Stara Zagora, Bulgaria
Centre Hospitalier Universitaire Estaing
🇫🇷Clermont-Ferrand, Puy-de-Dôme, France
Heritage Medical Research Centre
🇨🇦Calgary, Alberta, Canada
CHU Saint-Eloi
🇫🇷Montpellier, Occitanie, France
McGill University Health Centre
🇨🇦Montréal, Quebec, Canada
Vitaz
🇧🇪Sint-Niklaas, Oost-Vlaanderen, Belgium
Algemeen Ziekenhuis Maria Middelares
🇧🇪Gent, Oost-Vlaaderen, Belgium
Guizhou Provincial People's Hospital
🇨🇳Guiyang, Guizhou, China
Centre Hospitalier Universitaire de Rennes
🇫🇷Rennes, Ille-et-Vilaine, France
CHRU de Besançon - Hôpital Jean-Minjoz
🇫🇷Besançon, Franche-Comté, France
Hôpitaux Universitaires Paris Nord Val-de-Seine - Hôpital Beaujon
🇫🇷Clichy, Ile-de-France, France
Pontificia Universidad Católica de Chile - Escuela de Medicina
🇨🇱Santiago, Chile
Consultorio de la Dra. Maria Sarai Gonzalez Huezo
🇲🇽Metepec, Mexico
Hospital Universitario "Dr. Jose Eleuterio Gonzalez" (Servicio de Gastroenterologia)
🇲🇽Monterrey, Mexico
Hospital Universitario Dr. José Eleuterio González
🇲🇽Monterrey, Mexico
PanAmerican Clinical Research S.A. de C.V.
🇲🇽Querétaro, Mexico
Centre de Médecine Métabolique de Lanaudière
🇨🇦Terrebonne, Quebec, Canada
Hôpitaux Universitaires Paris-Sud - Hôpital Paul Brousse
🇫🇷Villejuif, Ile-de-France, France
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
🇮🇹Roma, Italy
Università degli Studi di Napoli Federico II
🇮🇹Napoli, Italy
Hadassah University Hospital Ein Kerem
🇮🇱Jerusalem, Jerusalem District, Israel
Cliniques Universitaires Saint-Luc
🇧🇪Brussel, Belgium
Centre Hospitalier Universitaire de Liège Site Sart Tilman
🇧🇪Liège, Belgium
The Sixth People's Hospital of Zhengzhou
🇨🇳Zhengzhou, Henan, China
Hospital Universitario Doctor José Eleuterio Gonzalez
🇲🇽Monterrey, Nuevo León, Mexico
Hospital Ernesto Dornelles
🇧🇷Porto Alegre, Rio De Janeiro, Brazil
Medical Center Medica Plus
🇧🇬Veliko Tarnovo, Bulgaria
Tianjin Third Central Hospital
🇨🇳Tianjin, China
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
🇧🇷Cerqueira César, Sao Paulo, Brazil
Fundação Faculdade Regional de Medicina de São José do Rio Preto
🇧🇷São José Do Rio Preto, São Paulo, Brazil
Liverpool Hospital
🇦🇺Liverpool, New South Wales, Australia
Hospital de Clínicas de Porto Alegre
🇧🇷Porto Alegre, Rio Grande Do Sul, Brazil
Zhengzhou First People's Hospital
🇨🇳Zhengzhou, Henan, China
Affiliated Hospital of Nantong University
🇨🇳Nantong, Jiangsu, China
The Second Hospital of Nanjing
🇨🇳Nanjing, Jiangsu, China
Medical Care and Research S.A. de C.V.
🇲🇽Mérida, Yucatan, Mexico
The Fifth People's Hospital of Suzhou
🇨🇳Suzhou, Jiangsu, China
Wuxi No.5 People's Hospital
🇨🇳Wuxi, Jiangsu, China
Third People's Hospital of Zhenjiang
🇨🇳Zhenjiang, Jiangsu, China
Azienda Ospedaliero-Universitaria Citta della Salute e della Scienza di Torino
🇮🇹Torino, Italy
Investigaciones Medicas Cisneros
🇲🇽Monterrey, Nuevo León, Mexico
Centre Hosptitalier Universitaire d'Angers
🇫🇷Angers, Maine-et-Loire, France
Centre Hospitalier Universitaire Grenoble Alpes
🇫🇷Grenoble, Isère, France
PanAmerican Clinical Research Mexico - Cuernavaca
🇲🇽Cuernavaca, Morelos, Mexico
Centro de Investigación y Gastroenterología
🇲🇽Cuauhtémoc, Ciudad De México, Mexico
Centro de Investigacion y Gastroenterologia, S.C.
🇲🇽Ciudad de Mexico, Mexico
Instituto de Seguridad Social del Estado de Mexico y Municipios
🇲🇽Metepec, Mexico
Centro de Investigacion Medico Biologica y Terapia Avanzada
🇲🇽Guadalajara, Jalisco, Mexico
Research Site s.r.o.
🇨🇿Plzen, Czechia
CHU de Lille - Hôpital Claude Huriez
🇫🇷Lille, Hauts-de-France, France
Hôpital Hautepierre
🇫🇷Strasbourg, Bas-Rhin, France
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
🇩🇪Mainz, Rheinland-Pfalz, Germany
Hôpitaux Universitaires Henri Mondor
🇫🇷Créteil, Ile-de-France, France
Centre Hospitalier Universitaire De Nantes - Hôpital Nord Laennec
🇫🇷Nantes, Nantes Cedex 1, France
Universitätsklinikum Carl Gustav Carus Dresden
🇩🇪Dresden, Sachsen, Germany
Radboud Universitair Medisch Centrum
🇳🇱Nijmegen, Gelderland, Netherlands
Western Galilee Hospital-Nahariya
🇮🇱Nahariya, Northern District, Israel
Hospital Regional de Alta Especialidad de Zumpango
🇲🇽Zumpango, Mexico
Carmel Medical Center
🇮🇱Haifa, Haifa District, Israel
The First Hospital of Jilin University
🇨🇳Changchun, China
Shaare Zedek Medical Center
🇮🇱Jerusalem, Jerusalem District, Israel
William Osler Health System - Brampton Civic Hospital
🇨🇦Brampton, Ontario, Canada
Peking University First Hospital
🇨🇳Beijing, Beijing, China
SYNEXUS Magyarország Egészségügyi Szolgáltató KFT
🇭🇺Budapest, Central Hungary, Hungary
The First Affiliated Hospital of Fujian Medical University
🇨🇳Fuzhou, Fujian, China
Synexus Magyarország Egészségügyi Szolgáltató Kft. - Debrecen
🇭🇺Debrecen, Hajdu-Bihar County, Hungary
Debreceni Egyetem Klinikai Központ Kenézy Gyula Campus
🇭🇺Debrecen, Hajdú-Bihar, Hungary
Royal Brisbane and Women's Hospital
🇦🇺Herston, Queensland, Australia
Gallipoli Medical Research Foundation
🇦🇺Greenslopes, Queensland, Australia
Gastroenterologische Gemeinschaftspraxis Herne
🇩🇪Herne, Nordrhein-Westfalen, Germany
Ziekenhuis Oost-Limburg - Campus Sint-Jan
🇧🇪Genk, Limburg, Belgium
Universitair Ziekenhuis Gent
🇧🇪Gent, Oost-Vlaanderen, Belgium
Digestive & Liver Disease Specialists
🇺🇸Norfolk, Virginia, United States
Inova Medical Group - Fairfax Hospital
🇺🇸Falls Church, Virginia, United States
Emeritas Research Group
🇺🇸Leesburg, Virginia, United States
Amsterdam Universitair Medische Centra - Vrije Universiteit Medisch Centrum
🇳🇱Amsterdam, Noord-Holland, Netherlands
Franciscus Gasthuis & Vlietland
🇳🇱Rotterdam, Netherlands
Synexus - Wrocław
🇵🇱Wrocław, Dolnoslaskie, Poland
ID Clinic
🇵🇱Mysłowice, Silesian Voivodeship, Poland
Synexus - Poznań
🇵🇱Poznań, Wielkopolskie, Poland
Synexus - Częstochowa
🇵🇱Czestochowa, Śląskie, Poland
Hospital de Braga
🇵🇹Braga, Portugal
Centro Hospitalar Universitário De São João
🇵🇹Porto, Portugal
Hospital Pedro Hispano
🇵🇹Senhora Da Hora, Portugal
Synexus - Helderberg Clinical Research Centre - Somerset West
🇿🇦Somerset West, Western Cape, South Africa
Fundación de Investigación de Diego Clinical Research
🇵🇷San Juan, Puerto Rico
Hospital Clínic de Barcelona
🇪🇸Barcelona, Spain
Synexus Clinical Research SA- Watermeyer
🇿🇦Pretoria, South Africa
Hospital Clínico Universitario de Santiago
🇪🇸Santiago de Compostela, La Coruña, Spain
Hospital Universitario Puerta de Hierro - Majadahonda
🇪🇸Majadahonda, Madrid, Spain
Hospital Clinico Universitario Lozano Blesa
🇪🇸Zaragoza, Spain
Panthera Biopartners - Manchester
🇬🇧Manchester, England, United Kingdom
Medical Center Edelweiss Medics, LLC
🇺🇦Kyiv, Ukraine
Hospital Universitario Virgen del Rocío
🇪🇸Sevilla, Spain
Consorci Hospital General Universitari de València
🇪🇸Valencia, Spain
Hospital Universitario Rio Hortega
🇪🇸Valladolid, Spain
Medical Center Center of Family Medicine Plus, LLC
🇺🇦Kyiv, Ukraine
King's College Hospital NHS Foundation Trust
🇬🇧London, England, United Kingdom
Barts Health NHS Trust
🇬🇧London, England, United Kingdom
Objective Health - Birmingham Gastroenterology Associates
🇺🇸Birmingham, Alabama, United States
Mayo Clinic - Rochester
🇺🇸Rochester, Minnesota, United States
Azienda Ospedaliero-Universitaria Maggiore della Carità di Novara
🇮🇹Novara, Italy
UOSD Interdipartimentale Degenza Medica a ciclo breve
🇮🇹Roma, Italy
Hôpital Universitaire Pitié Salpêtrière
🇫🇷Paris, Ile-de-France, France
Hôpital Saint-Antoine
🇫🇷Paris, Ile-de-France, France
CHU de Limoges
🇫🇷Limoges, Limousin, France
Hôpitaux de Brabois
🇫🇷Vandœuvre-lès-Nancy, Lorraine, France
Hôpital de la Croix Rousse
🇫🇷Lyon, Rhône-Alpes, France
EPIMED
🇩🇪Berlin, Germany
Universitätsklinikum Düsseldorf
🇩🇪Northeim, Germany
Complejo Hospitalario Torrecárdenas
🇪🇸Almería, Spain
Hospital de la Santa Creu i Sant Pau
🇪🇸Barcelona, Spain
Hospital Germans Trias i Pujol
🇪🇸Badalona, Spain
Hospital Universitari Vall d'Hebrón
🇪🇸Barcelona, Spain
Hospital Universitario Virgen de la Victoria
🇪🇸Málaga, Spain
Complejo Hospitalario De Pontevedra
🇪🇸Pontevedra, Spain
Hospital General Universitario Gregorio Marañón
🇪🇸Madrid, Spain
Hospital Clínico Universitario de Valencia
🇪🇸Valencia, Spain
Hospital Universitario Miguel Servet
🇪🇸Zaragoza, Spain
Options Health Research
🇺🇸Tulsa, Oklahoma, United States
Weill Cornell Medical College
🇺🇸New York, New York, United States
University of Rochester Medical Center
🇺🇸Rochester, New York, United States
Richmond University Medical Center
🇺🇸Staten Island, New York, United States
John Hunter Hospital
🇦🇺New Lambton, New South Wales, Australia
Gastroenterology Associates of Western Michigan
🇺🇸Wyoming, Michigan, United States
University of Michigan Health-West Hospital
🇺🇸Wyoming, Michigan, United States
Precision Research Institute
🇺🇸Chula Vista, California, United States
GW Research
🇺🇸Chula Vista, California, United States
Tandem Clinical Research
🇺🇸Marrero, Louisiana, United States
Louisiana Research Center LLC
🇺🇸Shreveport, Louisiana, United States
Palmetto Clinical Research
🇺🇸Summerville, South Carolina, United States
Clinovacare Medical Clinical Research Center
🇺🇸West Columbia, South Carolina, United States
Hi Tech and Global Research, LLC
🇺🇸Coral Gables, Florida, United States
Tampa Bay Medical Research
🇺🇸Clearwater, Florida, United States
Accel Research Sites
🇺🇸Maitland, Florida, United States
Florida Vascular Research
🇺🇸Miami, Florida, United States
Doral Medical Research, LLC
🇺🇸Hialeah, Florida, United States
D&H National Research Centers
🇺🇸Miami, Florida, United States
Future Care Solution
🇺🇸Miami, Florida, United States
IMIC Research - International Medical Investigations Centers
🇺🇸Palmetto Bay, Florida, United States
NAPA Research
🇺🇸Pompano Beach, Florida, United States
Genoma Research Group
🇺🇸Miami, Florida, United States
Eminat, LLC
🇺🇸Plantation, Florida, United States
GI Alliance - Gastroenterology Associates of Florida - Wellington
🇺🇸Wellington, Florida, United States
Covenant Metabolic Specialists LLC - Sarasota
🇺🇸Sarasota, Florida, United States
Florida Medical Clinic - Zephyrhills
🇺🇸Zephyrhills, Florida, United States
University of Iowa Hospitals and Clinics
🇺🇸Iowa City, Iowa, United States
Tampa General Hospital
🇺🇸Tampa, Florida, United States
Lucas Research, Inc
🇺🇸Morehead City, North Carolina, United States
Excel Medical Clinical Trials, LLC
🇺🇸Boca Raton, Florida, United States
PanAmerican Clinical Research - US Headquarters
🇺🇸Brownsville, Texas, United States
Optimus U Corporation
🇺🇸Miami, Florida, United States
USPA Advance Concept Medical Research Group
🇺🇸Miami, Florida, United States
Schiff Center for Liver Diseases
🇺🇸Miami, Florida, United States
Gastro Clinic
🇺🇸El Paso, Texas, United States
GI Alliance - Mansfield
🇺🇸Mansfield, Texas, United States
Cleveland Clinic Florida
🇺🇸Weston, Florida, United States
Palmetto Research
🇺🇸Hialeah, Florida, United States
Metropolitan Gastroenterology Associates - Metairie
🇺🇸Metairie, Louisiana, United States
Washington University School of Medicine in St. Louis
🇺🇸Saint Louis, Missouri, United States
Pinnacle Research Group
🇺🇸Anniston, Alabama, United States
Digestive Health Specialist of the Southeast
🇺🇸Dothan, Alabama, United States
North Alabama GI Research Center llc
🇺🇸Madison, Alabama, United States
The Institute For Liver Health - Chandler
🇺🇸Chandler, Arizona, United States
Arizona Liver Health - Peoria
🇺🇸Peoria, Arizona, United States
Saint Joseph's Hospital and Medical Center
🇺🇸Phoenix, Arizona, United States
Arizona Digestive Health - Sun City
🇺🇸Kansas City, Kansas, United States
Adobe Gastroenterology
🇺🇸Tucson, Arizona, United States
Arkansas Gastroenterology
🇺🇸North Little Rock, Arkansas, United States
Arizona Liver Health
🇺🇸Tucson, Arizona, United States
Arkansas Diagnostic Center
🇺🇸Little Rock, Arkansas, United States
Office of Franco Felizarta, MD
🇺🇸Bakersfield, California, United States
Fomatmedicalresearch
🇺🇸Camarillo, California, United States
SC Clinical Research
🇺🇸Garden Grove, California, United States
The Clinical Trials Network - Gastro Care Institute
🇺🇸Lancaster, California, United States
Cure Clinical Research, LLC
🇺🇸Fountain Valley, California, United States
Velocity Clinical Research, Chula Vista
🇺🇸Chula Vista, California, United States
National Research Institute - Santa Ana
🇺🇸Huntington Park, California, United States
National Research Institute - Panorama City
🇺🇸Panorama City, California, United States
California Liver Reearch
🇺🇸Pasadena, California, United States
TriWest Research Associates
🇺🇸El Cajon, California, United States
Prospective Research Innovations Inc.
🇺🇸Rancho Cucamonga, California, United States
Inland Empire Liver Foundation
🇺🇸Rialto, California, United States
Cadena Care Institute
🇺🇸Poway, California, United States
Silicon Valley Research Institute
🇺🇸San Jose, California, United States
Clinical Trial Management Services
🇺🇸Thousand Oaks, California, United States
San Fernando Valley Health Institute
🇺🇸Van Nuys, California, United States
South Denver Gastroenterology - Swedish Medical Center Office
🇺🇸Englewood, Colorado, United States
Gastro Health - Galloway
🇺🇸Miami, Florida, United States
Northwestern University
🇺🇸Chicago, Illinois, United States
Grand Teton Research Group, PLLC
🇺🇸Idaho Falls, Idaho, United States
Gastroenterology Associates - Baton Rouge
🇺🇸Baton Rouge, Louisiana, United States
The Johns Hopkins Hospital
🇺🇸Baltimore, Maryland, United States
Gastro Center of Maryland - Columbia
🇺🇸Columbia, Maryland, United States
Mid-Atlantic GI Research
🇺🇸Greenbelt, Maryland, United States
Gastrointestinal (GI) Associates L.L.P.
🇺🇸Columbia, Missouri, United States
SKYCRNG - Quinn Healthcare
🇺🇸Ridgeland, Mississippi, United States
Veterans Affairs Pittsburgh Healthcare System - University Drive Campus
🇺🇸Pittsburgh, Pennsylvania, United States
Rapid City Medical Center
🇺🇸Rapid City, South Dakota, United States
Gastro One - Germantown Office - Wolf Park Drive
🇺🇸Germantown, Tennessee, United States
Liver Center of Texas
🇺🇸Dallas, Texas, United States
GI Alliance - Texas Digestive Disease Consultants - Fort Worth - Downtown
🇺🇸Dallas, Texas, United States
Soma Clinical Trials
🇺🇸Denison, Texas, United States
South Texas Research Institute - Edinburg
🇺🇸Edinburg, Texas, United States
Care United Medical Center - Forney
🇺🇸Forney, Texas, United States
Brooke Army Medical Center
🇺🇸Fort Sam Houston, Texas, United States
Houston Methodist Hospital
🇺🇸Houston, Texas, United States
Digestive Health Associates of Texas - Rockwall
🇺🇸Garland, Texas, United States
Advanced Medical Trials
🇺🇸Georgetown, Texas, United States
Lone Peak Family Health
🇺🇸Draper, Utah, United States
Topography Health, Inc.
🇺🇸Manassas, Virginia, United States
Liver Institute Northwest
🇺🇸Seattle, Washington, United States
Froedtert and Medical College of Wisconsin
🇺🇸Milwaukee, Wisconsin, United States
Hospital De Alta Complejidad en Red El Cruce
🇦🇷Buenos Aires, Buenos Aries, Argentina
Concord Repatriation General Hospital
🇦🇺Concord, New South Wales, Australia
Hospital Británico de Buenos Aires
🇦🇷Buenos Aires, Argentina
Nepean Hospital
🇦🇺Penrith, New South Wales, Australia
Campbelltown Hospital
🇦🇺Liverpool, New South Wales, Australia
Monash Medical Centre
🇦🇺Clayton, Victoria, Australia
Universitair Ziekenhuis Antwerpen
🇧🇪Edegem, Antwerpen, Belgium
Hôpital l'Archet
🇫🇷Nice, Provence-Alpes-Côte d'Azur, France
Uniklinik Köln
🇩🇪Köln, Germany
Soroka Medical Center
🇮🇱Be'er Sheva, Southern District, Israel
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
🇮🇹Milan, Italy
Azienda Ospedaliero-Universitaria di Bologna Policlinico Sant Orsola-Malpighi
🇮🇹Bologna, Italy
Rambam Health Care Campus
🇮🇱Haifa, Israel
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone
🇮🇹Palermo, Italy
Oaxaca Site Management Organization S.C.
🇲🇽Oaxaca, Mexico
Ziekenhuis Bernhoven
🇳🇱Uden, North Brabent, Netherlands
Universitair Medisch Centrum Utrecht
🇳🇱Utrecht, Netherlands
Synexus - Łódź
🇵🇱Łódź, Łódzkie, Poland
Hospital da Senhora da Oliveira - Guimarães
🇵🇹Guimarães, Braga, Portugal
Centro Hospitalar Universitário Lisboa Norte - Hospital De Santa Maria
🇵🇹Lisboa, Portugal
Unidade Local Saúde Alto Minho - Hospital de Santa Luzia
🇵🇹Viana Do Castelo, Portugal
Synexus - Mediclinic Southern Africa - Constantiaberg
🇿🇦Cape Town, Western Cape, South Africa
Sefako Makgatho Health Sciences University
🇿🇦Pretoria, Gauteng, South Africa
Hospital Universitario Marqués de Valdecilla
🇪🇸Santander, Cantabria, Spain
Consorci Corporació Sanitària Parc Taulí de Sabadell
🇪🇸Sabadell, Barcelona, Spain
Hospital Universitario Son Espases
🇪🇸Palma De Mallorca, Balearic Islands, Spain
Hospital Universitario Fundación Alcorcón
🇪🇸Alcorcón, Madrid, Spain
Complejo Asistencial Universitario de Leon
🇪🇸León, Spain
Medical Center Medbud-Clinic, LLC
🇺🇦Kyiv, Ukraine
Panthera Biopartners - Preston
🇬🇧Preston, England, United Kingdom
Sheffield Teaching Hospitals NHS FT
🇬🇧Sheffield, England, United Kingdom
Stanford University Medical Center
🇺🇸Redwood City, California, United States
Yale School of Medicine
🇺🇸New Haven, Connecticut, United States
AdventHealth Transplant Institute
🇺🇸Orlando, Florida, United States
Digestive and Liver Center of Florida - Orlando
🇺🇸Orlando, Florida, United States
Saint Luke's Hospital of Kansas City
🇺🇸Kansas City, Missouri, United States
Kansas City Research Institute
🇺🇸Kansas City, Missouri, United States
Gastroenterology of the Piedmont, PA - Salem Office
🇺🇸Winston-Salem, North Carolina, United States
Medical University of South Carolina
🇺🇸Charleston, South Carolina, United States
Accelemed Research Institute
🇺🇸Austin, Texas, United States
Pinnacle Clinical Research - Austin
🇺🇸Austin, Texas, United States
GI Select Health Research, LLC
🇺🇸Richmond, Virginia, United States
Hunter Holmes Mcguire Veterans Affairs Medical Center - Richmond
🇺🇸Richmond, Virginia, United States
Virginia Commonwealth University
🇺🇸Richmond, Virginia, United States
University of Kentucky
🇺🇸Lexington, Kentucky, United States
Southwest Gastroenterology Associates
🇺🇸Albuquerque, New Mexico, United States
Kansas Medical Clinic - Gastroenterology
🇺🇸Topeka, Kansas, United States
GI Alliance - Bay Area Gastroenterology - Webster
🇺🇸Webster, Texas, United States
Hospital San Juan de Dios de La Serena
🇨🇱La Serena, Coquimbo, Chile
American Research Institute, INC
🇺🇸Cutler Bay, Florida, United States
Tranquil Clinical Research
🇺🇸Webster, Texas, United States
Toronto Digestive Disease Associates
🇨🇦Vaughan, Ontario, Canada
Guangzhou First People's Hospital
🇨🇳Guangzhou, Guangdong, China
Hôpital Cochin
🇫🇷Paris, France
Universitätsklinikum des Saarlandes
🇩🇪Homburg, Saarland, Germany
Gastroenterologie am Bayerischen Platz
🇩🇪Berlin, Germany
Digestive Health Research of North Texas
🇺🇸Wichita Falls, Texas, United States
Koncord Research-McAllen LLC
🇺🇸McAllen, Texas, United States
Clinique Pasteur
🇫🇷Toulouse, Occitanie, France
Royal Free London NHS Foundation Trust
🇬🇧London, United Kingdom
Medizinische Universität Innsbruck
🇦🇹Innsbruck, Tyrol, Austria