MedPath

Safety and Efficacy of Insulin Detemir in Combination With OADs in Type 2 Diabetes

Phase 3
Completed
Conditions
Diabetes
Diabetes Mellitus, Type 2
Registration Number
NCT00592527
Lead Sponsor
Novo Nordisk A/S
Brief Summary

This trial is conducted in Asia.

The aim of this trial is to evaluate the blood glucose achieved with insulin detemir as add-on to current oral antidiabetic drug (OAD) treatment in subjects with type 2 diabetes.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
132
Inclusion Criteria
  • Type 2 diabetes for at least 12 months since diagnosis
  • Insulin naive subjects
  • OAD treatment for at least 4 months with max. two OAD treatments
  • Body mass index below 30.0 kg/m2
  • HbA1c between 7.0-11.0%
Exclusion Criteria
  • OAD treatment with three or more OADs
  • Secondary diabetes
  • Known hypoglycaemia unawareness or recurrent major hypoglycaemia as judged by the Investigator
  • Uncontrolled hypertension
  • Known or suspected allergy to trial product or related products

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
HbA1cafter 20 weeks of treatment
Secondary Outcome Measures
NameTimeMethod
Incidence of adverse events
Fasting plasma glucose (FPG)
Within-subject variation
Change in body weight

Trial Locations

Locations (1)

Novo Nordisk Investigational Site

🇮🇳

Nagpur, India

© Copyright 2025. All Rights Reserved by MedPath