The Efficacy of Three Months-prednisolone Therapy for Chronic Eosinophilic Pneumonia

Phase 4

Completed

• Conditions: Eosinophilic Pneumonia; Chronic Disease
• Interventions: Drug: prednisolone 0.5 mg/kg/day for six months; Drug: prednisolone 0.5 mg/kg/day for three months

• Registration Number: NCT00632554
• Lead Sponsor: Hamamatsu University

Brief Summary

A comparison of 3 months-prednisolone administration with 6 months-prednisolone therapy in the treatment of chronic eosinophilic pneumonia. Three months-prednisolone administration may be as effective as 6 months-therapy.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2008-02-28
• Study First Submitted QC: 2008-02-28
• Study First Posted: 2008-03-10
• Study Start: 2008-06
• Primary Completion: 2010-03
• Study Completion: 2010-03
• Status Verified: 2014-09
• Last Update Submitted: 2014-09-18
• Last Update Posted: 2014-09-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Biopsy-proven chronic eosinophilic pneumonia

Exclusion Criteria

• Patients who received oral glucocorticosteroid (more than 10 mg)
• Immunosuppressive drug

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
2	prednisolone 0.5 mg/kg/day for six months	prednisolone therapy for six months
1	prednisolone 0.5 mg/kg/day for three months	prednisolone therapy for three months

Primary Outcome Measures

Name	Time	Method
Efficacy of 3 versus 6 months-prednisolone therapy for chronic eosinophilic pneumonia	Three years

Secondary Outcome Measures

Name	Time	Method
Safety of 3 versus 6 months-prednisolone therapy for chronic eosinophilic pneumonia	Three years

Trial Locations

Locations (1)

Hamamatsu University School of Medicine; 🇯🇵 Hamamatsu, Japan