We Compared the Covid-19 Acute Respiratory Distress Syndrome (ARDS) Patients Who Applied Prone Positioning for16-24 Hours vs 24-48 Hours

Completed

• Conditions: Oxygenation Indices; Hypoxia; Morality
• Interventions: Other: prone positioning

• Registration Number: NCT06530095
• Lead Sponsor: Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Brief Summary

The goal of this study is to understand if there is any improvement on oxygenation of patients diagnosed with Covid-19 ARDS patients when we extend the duration of prone positioning.

Second outcome of the study is to investigate mortality of patients when we extend the duration of prone positioning.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-03
• Primary Completion: 2023-01-03
• Study Completion: 2024-02-15
• Status Verified: 2024-07
• Study First Submitted: 2024-07-30
• Study First Submitted QC: 2024-07-30
• Last Update Submitted: 2024-07-30
• Study First Posted: 2024-07-31
• Last Update Posted: 2024-07-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 350

Inclusion Criteria

COVİD 19 ARDS patients patients who have been intubated for 48 hours and more

Exclusion Criteria

Pediatric patients Patients who extubated in less than 48 hours Patients with Lung and pleural malignancies

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group B	prone positioning	Patients who have been in prone positioning for 24-48 hours
Group A	prone positioning	Patients who have been in prone positioning for 16-24 hours

Primary Outcome Measures

Name	Time	Method
Oxygenation Index	48 hours	Oxygenation index is calculated as OI = MAP × Fio2 × 100 / Pao2, where MAP indicates mean airway pressure and Fio2 indicates fraction of inspired oxygen
Oxygen Saturation Index (OSI)	48 hours	OSI is calculated by dividing the product of mean airway pressure (MAP) and FiO2 with SpO2

Secondary Outcome Measures

Name	Time	Method
ICU mortality	28 days	mortality rates during patients admission in the ICU

Trial Locations

Locations (1)

Bakirkoy Dr Sadi konuk Research and Training hospital; 🇹🇷 Istanbul, Turkey