Clinical study of Yiqi Huoxue Herbs on Improving Exercise Tolerance in patients with Stable Coronary Artery Disease

Xiyuan Hospital, China Academy of Chinese Medical Sciences0 个研究点开始时间: 待定最近更新: 2023年2月20日

试验速览

暂无简介。

•(1) Aged between 18 to 75 years.
•(2) Patients with stable coronary artery disease, coronary artery stenosis >= 50% identified by coronary angiography or coronary computed tomography angiography, or with stable clinical condition >= 3 months after percutaneous coronary intervention treatment (with low or moderate risk of sports rehabilitation);
•(3) Patients with symptoms of fatigue or shortness of breath , or the typical symptoms of effort angina, or with a history of previous myocardial infarction, or with documented heart failure diagnosis (including heart failure with preserved ejection fraction);
•(4) Patients providing written informed consents.

•(1) Left main coronary artery stenosis (5th segment) >= 50% or proximal left anterior descending coronary artery stenosis (6th segment) > 70%;
•(2) Severe aortic stenosis, acute aortic dissection, acute myocarditis or pericarditis, aneurysm, severe pulmonary hypertension, acute pulmonary embolism, pulmonary infarction, bullae, emphysema, respiratory failure and other cardiopulmonary diseases, or heart Failure (NYHA >= III);
•(3) Acute cerebrovascular disease;
•(4) Uncontrolled blood pressure with the systolic blood pressure >= 160mmHg and/or diastolic blood pressure >= 100mmHg;
•(5) Uncontrolled arrhythmia with clinical symptoms or hemodynamic disorders;
•(6) Severe primary hepatic, renal, hematopoietic system, acute infectious diseases, mental disorders, or other diseases that are not suitable for cardiopulmonary exercise test;
•(7) Pregnant, planning to pregnant or lactating women;
•(8) Underwent major surgical intervention on the skull or chest and abdomen within 4 weeks and with a bleeding tendency;
•(9) Participated in other clinical trials within 1 month;
•(10) Allergic to the test drug or its known components.

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