Evaluation of activity of cytochrome P450 2D6 (CYP 2D6) in normal healthy adult Maharashtrian, Gujarati and Marwari subjects (Western India) by phenotyping and genotyping
Phase 4
Completed
- Registration Number
- CTRI/2010/091/000030
- Lead Sponsor
- Department of Biotechnology Govt of India New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 600
Inclusion Criteria
Adult heatlhy male and female, 18 to 45 years with no history of chronic illness and non-smokers and not on any medications metabolised by CYP4502D6 and normal on physical examination who are willing to give informed consent to participate in the study
Exclusion Criteria
history of git, renal, liver, cardiovascular, respiratory and endocrine diseases.
unwilling to comply protocol requirements.
Dextromethorphan use in last 7 days.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To classify western indian population into poor or rapid metabolisers by phenotyping and genotyping correlationTimepoint: Single
- Secondary Outcome Measures
Name Time Method ILTimepoint: NI