Study of the effects of omega-3 fatty acids supplementation on cigarette craving, urinary cotinine levels and oxidative stress index in heavy smokers
Not Applicable
- Conditions
- Heavy smoker.Exposure to tobacco smoke
- Registration Number
- IRCT2016092929508N5
- Lead Sponsor
- Vice chancellor for research, Urmia University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 54
Inclusion Criteria
heavy smokers (a smoker who reports consuming 20 cigarettes or more per day); level of dependence above moderate (Fagerström test for nicotine dependence – FTND = 7 points); depression below mild (Depression Anxiety Stress Scale 21 for depression - DASS 21 < 9 points); anxiety below moderate ( DASS 21 < 9 points); stress below moderate ( DASS 21 <18 points); average motivation to quit smoking (Richmond test – RT > 5 points);
Exclusion criteria:psychiatric and neurodegenerative disorders; abusive use of alcohol or other substances
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Tobacco craving. Timepoint: before intervention, 3 months after intervention. Method of measurement: tobacco craving questionair- short form.;Urinary cotinine. Timepoint: before intervention, 3 months after intervention. Method of measurement: nanogram/liter.;Oxidative stress index. Timepoint: before intervention, 3 months after intervention. Method of measurement: micromol.;Total oxidant status (TOS). Timepoint: before intervention, 3 months after intervention. Method of measurement: µm.;Total antioxidant capacity (TAC). Timepoint: before intervention, 3 months after intervention. Method of measurement: µm.
- Secondary Outcome Measures
Name Time Method icotine dependence. Timepoint: before intervention, 3 months after intervention. Method of measurement: fagesterstrom test.;Sigarette use per day. Timepoint: before intervention, 3 months after intervention. Method of measurement: interview.