Does endometriosis affect egg and embryo quality ?
Not Applicable
- Conditions
- Health Condition 1: N80-N98- Noninflammatory disorders of female genital tract
- Registration Number
- CTRI/2020/04/024728
- Lead Sponsor
- DR Manish Banker
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age: 21-35 yrs with indication for IVF
Unilateral endometrioma with mean diameter <50 mm on TVS
Endometrioma defined as: cystic mass with min diameter 10mm with regular margins, low echogenic fluid content without projections
To differentiate from functional cysts: presence of endometrioma on atleast on pelvic scan performed 2 months before ICSI
Diagnosis made on typical USG features/H/ O previous laparoscopy/aspiration/HPE
No H/O previous surgery on the affected ovary
No severe cause of male infertility
Exclusion Criteria
Non endometriotic cysts/ cysts resolving after medical management
Atypical/doubtful diagnosis of cysts
Medical management for endometriosis
Accidental follicular fluid contamination with endometrioma content
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the effect of endometrioma on oocyte and embryo quality. Women with unilateral endometriosis undergoing IVF were included in the study. Oocytes from the ovary were compared with those from the unaffected (normal) ovary (acting as control) with respect to: <br/ ><br>Number of oocytes retrieved <br/ ><br>Number of mature oocytes & Maturation rate <br/ ><br>Number of blastocysts obtained & Blastulation rate <br/ ><br>Timepoint: At baseline <br/ ><br>Number of oocytes retrieved <br/ ><br>Number of mature oocytes & <br/ ><br>Maturation rate <br/ ><br>At 1 week <br/ ><br>Number of blastocysts obtained & Blastulation rate <br/ ><br>
- Secondary Outcome Measures
Name Time Method Pregnancy ratesTimepoint: study period