Clinical Research on the Predictive Effect of Neonatal Morbidities on the Poor Outcomes to Very Low Birth-weight and Extremely Low Birth-weight Infants
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 834
- Primary Endpoint
- visual impairment
Study Overview
Brief Summary
From November 2014 to October 2015, a multi-centers retrospective study was conducted to collect compliance, and 8 three-level hospitals from China were included. The infants survived to a postmenstrual age of 36 week with birth weight less than 1500g and without congenital disease. The birth weight, gestational age, morbidities and poor outcomes( death, cerebral palsy, cognitive, et al) were recorded. Data were analyzed with Chi-square test to observe the relationship between morbidities and poor outcomes. And the predictive effect on the number of the top three morbidities were analyzed by Logistic regression analysis.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 1 Month to 12 Months (Child)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •From November 2014 to October 2015, a multi-centers retrospective study was conducted to collect compliance, and 8 three-level hospitals from China were included. The infants survived to a postmenstrual age of 36 week with birth weight less than 1500g.
Exclusion Criteria
- •The very low birth weight infants didn't have any congenital disease.
Outcomes
Primary Outcomes
visual impairment
Time Frame: 1 year
do not pass okineticnystagmus
cognitive delay
Time Frame: 1 year
mental development index(MDI）\<70
hearing impairment
Time Frame: 1 year
do not pass auditory brainstem response (ABR)
Secondary Outcomes
No secondary outcomes reported
Investigators
yangjie
Director of Dept of Neonatology
Guangdong Women and Children Hospital