A comparative study of upper limb function and cost effectiveness after collagenase injection and aponeurectomy for Dupuytren contracture
- Conditions
- Dupuytren contracture
- Registration Number
- JPRN-UMIN000029826
- Lead Sponsor
- agoya University
- Brief Summary
Participants comprised 52 patients in the Collagenase group and 26 patients in the Surgery group. Hand10 score was significantly better in the Collagenase group at 1 and 2 weeks. EQ-5D-5L score was significantly higher in the Collagenase group at 8 weeks. Mean direct cost was 248,000 yen higher in the Surgery group than in the Collagenase group.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 78
Not provided
1) Patients who had treated Dupuytran contracture in the past and recurred 2) Patients with a history of hypersensitivity to components of injectable collagenase 3) Patients who may be pregnant or pregnant, patients wishing for pregnancy during this clinical study or patients who may be pregnant, lactating patients 4) Patients who are receiving anticoagulant, antiplatelet drug (excluding aspirin at 150 mg / day or less) within 7 days before treatment 5) Patients who are separately participating in intervention tests such as trials and clinical trials 6) Patients who have difficulty understanding and answering inquiries of documents consent in Japanese, 7) Other Research Responsibilities (Sharing) Patients judged inappropriate for doctors to conduct this clinical study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method