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临床试验/NCT04863469
NCT04863469Unknown不适用

Neurocognitive Optimization and Enhancement for Brain Health and Performance

Walter Reed Army Institute of Research (WRAIR)2 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2020年10月20日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
66
试验地点
2
主要终点
Time to Failure Test

研究概览

简要总结

Brain-Physical Optimization Conditioning (B-POC) aims to enhance physical performance by expanding the traditional focus of endurance training from purely physical training to the domain of cognitive endurance (Staiano et al., 2015; Dallaway et al., 2017). The current study seeks to isolate neurocognitive mechanisms of performance, particularly under high stress (e.g., physical or cognitive load) conditions, and to develop corresponding cognitive optimization tools.

详细描述

Brain-Physical Optimization Conditioning (B-POC) aims to enhance physical performance by expanding the traditional focus of endurance training from purely physical training to the domain of cognitive endurance (Staiano et al., 2015; Dallaway et al., 2017). B-POC uses an acute mentally fatiguing task during routine exercise with the aim of optimizing the effects of physical endurance (e.g., aerobic exercise). B-POC differs from other types of cognitive training by increasing the cognitive demands of a specific concurrent task rather than teaching a cognitive strategy and relying on task transfer effects. Similar to strengthening a muscle, cognitive trainings may be one means of increasing Soldier's cognitive capacity and improving performance (Walton et al., 2018).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy active duty Soldiers
  • 18-40 years old
  • Available for study duration

排除标准

  • Failure of an Army Physical Fitness/Combat Test (APFT/ACFT) test
  • On a physical profile that prevents them from 1) engaging in intense aerobic exercise, 2) running on a treadmill, 3) riding the stationary bike, and 4) performing a cognitive task on a computer screen.
  • Medically non-deployable
  • Impaired cognitive function due to medication, injury or illness,
  • Have been advised by a medical professional not to engage in aerobic exercise
  • Are a pregnant female

结局指标

主要结局

Time to Failure Test

时间窗: 7 weeks

The Time to Failure Test (TFT) requires participants to run on a treadmill with increases in either grade (0.5% increase) and speed (\~0.3-0.5 mph) every two minutes in an alternating format for the first 16 minutes, after which settings remain constant until self termination of the exercise. The TFT settings (work rate) are calculated from an individual's last 2 mile run time. Physiological load (heart rate, oxygen consumption) and perceived exertion (RPE) are measured throughout the TFT. The primary outcome is change in time to failure (minutes, seconds) on the endurance test from baseline to post0test (\~7 weeks).

次要结局

  • Dynamic Marksmanship(Pre-to-post ruck time (~30-90 minutes))

研究者

发起方
Walter Reed Army Institute of Research (WRAIR)
申办方类型
Fed
责任方
Sponsor

研究点 (2)

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