Collection and Preservation of Blood and Serum Specimens From HIV Positive or HIV Negative Patients for Multiple Collaborative Studies
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 2,000
- 试验地点
- 2
- 主要终点
- Plasma HIV RNA level
研究概览
简要总结
This study seeks to confidentially collect blood from HIV-positive individuals and HIV-negative controls to provide basic scientists with specimens for collaborative studies.
详细描述
HIV positive patients are currently the focus of multiple collaborative research studies, both at UCSF and other institutions. The aims of these research projects include improving the understanding of etiology, immunology, epidemiology and treatment of HIV. There are numerous requests from basic scientists at UCSF for collaborative studies on specimens, especially for blood, saliva and urine samples. Specimens may be used to test such things as virus characteristics, genotyping and/or phenotyping resistance, plasma drug concentrations, immune function or evidence of complications of HIV disease. The samples may also be tested for genetic factors that may be related to the course of HIV disease
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •HIV-1 antibody negative with similar characteristics to HIV-1 positive cohort
- •HIV-positive subjects naive to antiretroviral therapy
- •HIV-positive subjects stable on or off antiretroviral therapy for a minimum of 6 months
- •Good venous access
- •Able to provide informed consent
排除标准
- •Hemoglobin < 9g/dl
- •Hematocrit < 27%
- •Active treatment for cancer
- •Hospitalization or IV antibiotic use within the last 4 months
- •Immunosuppressive therapy within the last 4 months
研究组 & 干预措施
HIV Positive
HIV-1 positive subjects
HIV negative subjects
HIV-1 seronegative control group
结局指标
主要结局
Plasma HIV RNA level
时间窗: Ongoing
Viral load
次要结局
未报告次要终点