Skip to main content
MedPathMedPath Home
Clinical Trials/EUCTR2015-001211-13-IT
EUCTR2015-001211-13-IT
Active, not recruiting
Phase 1

IMAGING OF NEUROINFLAMMATION AND NEURODEGENERATION INALZHEIMER’S DISEASE - PRODROMAL AD

OSPEDALE SAN RAFFAELE0 sites38 target enrollmentNovember 5, 2020
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
Conditionsmild cognitive impairment and familiar Alzheimer diseaseMedDRA version: 22.1Level: LLTClassification code 10050727Term: RI scanSystem Organ Class: 100000004848Therapeutic area: Diseases [C] - Nervous System Diseases [C10]

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
mild cognitive impairment and familiar Alzheimer disease
Sponsor
OSPEDALE SAN RAFFAELE
Enrollment
38
Status
Active, not recruiting
Last Updated
5 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
November 5, 2020
End Date
TBD
Last Updated
5 years ago
Study Type
Interventional clinical trial of medicinal product
Sex
All

Investigators

Sponsor
OSPEDALE SAN RAFFAELE

Eligibility Criteria

Inclusion Criteria

  • •amnestic mild cognitive decline or genetic Alzheimer's disease (carriers of known PSEN1 and PSEN2 mutations) in asymptomatic or symptomatic disease phase (Clinical Dementia Rating Scale \< 1 and Mini Mental State Examinations \> 20\).
  • •Are the trial subjects under 18? no
  • •Number of subjects for this age range:
  • •F.1\.2 Adults (18\-64 years) yes
  • •F.1\.2\.1 Number of subjects for this age range 19
  • •F.1\.3 Elderly (\>\=65 years) yes
  • •F.1\.3\.1 Number of subjects for this age range 19

Exclusion Criteria

  • •presence of focal cerebral diseases, psychiatric, physic and metabolic disorders that can explain cognitive disorders; liver and/or kidney failures; pregnancy or breastfeeding; fertile women not assuming contraceptive therapy

Outcomes

Primary Outcomes

Not specified

Similar Trials

Active, not recruiting
Not Applicable
study of neuroinflammation in pathologies like Alzheimer, mild cognitive impairment, dementia and SLAmild cognitive impairment, Alzheimer disease,frontotemporal dementia, SLAMedDRA version: 14.1Level: LLTClassification code 10050727Term: RI scanSystem Organ Class: 100000004848Therapeutic area: Diseases [C] - Nervous System Diseases [C10]
EUCTR2012-004328-40-ITOSPEDALE S. RAFFAELE DI MILANO
Completed
Not Applicable
Analysing neuroinflammation and neurodegeneration in amyotrophic lateral sclerosis: quantitative imaging in a clinical trialMotor neuron disease, also referred to as amyotrophic lateral sclerosisNervous System DiseasesMotor neuron disease
ISRCTN40093015CHU de Nimes50
Recruiting
Not Applicable
Molecular Neuroimaging of Neuroinflammation in Neurodegenerative DementiasFrontotemporal Dementia
NCT02945774London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's40
Not yet recruiting
Not Applicable
Research on neurological disease using neuroimaging database and movement analysis
JPRN-UMIN000053240Tokyo Medical and Dental University800
Active, not recruiting
Phase 1
Imaging of neuroinflammation in frontotemporal dementia by means of PET-MRIFrontotemporal dementia (FTD), including symptomatic patients and presymptomatic individuals with genetic mutations predisposing to FTD at a later stage in life.Therapeutic area: Diseases [C] - Nervous System Diseases [C10]
EUCTR2020-002672-12-NLErasmus Medical Center32