Impact of dexmedetomidine on preventive noninvasive ventilation in thoracic trauma - VENDETTA

• Conditions: Thoracic trauma; Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]

• Registration Number: EUCTR2015-002210-71-FR
• Lead Sponsor: niversity Hospital Grenoble

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-07-27
• Last Update Posted: 26 October 2015

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Patient hospitalized in intensive care or USC
• Patient with a closed chest trauma not intubated (TTS score> 6)
• Patient row to social security
• Major Patient
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 16
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 4

Exclusion Criteria

• EVA Rest> 3
• Agitation with RASS> 2
• Patient on DEX or treated with an alpha 2 agonist in the last 8 hours
• Patients on home VNI (except for VS-PPC OSA)
• analgesia by epidural catheter
• Long-term treatment with neuroleptics
• Contraindications to the VNI
• Contraindications to the DEX

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified