A pilot study of metabolic syndrome metasynthesis of holistic medicine(homoeopathy) and integrative medicine.

This pilot study is an non randomized , active controlled trial to test the effectiveness of homoeopathic medicines and integrative medicine on metabolic syndrome. In this pilot study, we aim to study a minimum of 50 patients within a frame of 6 months where they will be observed for 6 months with follow-up after every 2 weeks. Patients will be selected based upon inclusion criteria if they are presenting with any 3 out of 5 criteria. We planned on dividing patients into 2 groups, on one we will administer homoeopathic remedies based on the totality of symptoms under the miasmatic background on the basis of homoeopathic philosophy. For another group we will consider Integrative medicine mainly focusing on patients who are coming to our study site with ongoing treatment with modern medicines, where we will only administer homoeopathic medicine according to individualization. We will not be giving any allopathic medicines. General Management will be advised through- DASH diet / low GI Diet / MUFAs / n-6 VLC-PUFAs and exercises. Data collection and instrument used- (i) Waist circumference- To be measured with a measuring tape by placing tape in a horizontal plane around abdomen at the level of iliac crest. Before measuring ensure the tape is sung but does not compress the skin and is parallel to the floor. Measurement is made at the end of normal expiration in centimeters or inches.(ii) Blood pressure- To be measured with a sphygmomanometer & stethoscope.(iii) Lab tests such as(only one from each of these, as per patients needs will be done)-(a)Blood sugar level- Fasting glucose test/ HbA1C test/ Oral Glucose Tolerance Test. (b)Triglyceride level- Triglycerides test (TGL) / Lipid profile test. (c)Low HDL-C level- High Density lipoprotein Cholesterol test(HDL-C test) / Lipid profile test. Lab tests will be done twice, before administration of medicine and at the end of 6 months or when the patient gets better(may vary).Individualized homoeopathic medicines, potency of the medicines, doses, and form of administration on patients will be recorded. In case of integrative approach, a list of conventional group of medicines acting along homoeopathic medicines in patients will be recorded. The primary outcome measures will be Waist circumference- ≥ 102 cm (40 inches) in males and ≥88 cm (35 inches) in females; Hypertension- ≥ 130/85 mm of hg; Blood sugar level- Fasting glucose test or HbA1C test or Oral Glucose Tolerance Test; Triglyceride level- Triglycerides test (TGL) or Lipid profile test; Low HDL-C level- High Density lipoprotein Cholesterol test(HDL-C test) or Lipid profile test; at 6 months of time period and secondary outcome measures will be Waist circumference- ≥ 102 cm (40 inches) in males and ≥88 cm (35 inches) in females; Hypertension- ≥ 130/85 mm of hg; at every 2 weeks for 6 months &  Blood sugar level- Fasting glucose test or HbA1C test or Oral Glucose Tolerance Test; Triglyceride level- Triglycerides test (TGL) or Lipid profile test; Low HDL-C level- High Density lipoprotein Cholesterol test(HDL-C test) or Lipid profile test; will be done twice before administration of homoeopathic medicine and after 6 months of administration of homoeopathic medicine.