Intra-abdominal hypertension and abdominal compartment syndrome in high risk patients admitted to the ICU: a prospective study
Completed
- Conditions
- Abdominale aandoeningen met risico op verhoogde buikdrukAbdominal hypertensionincreased belly pressure
- Registration Number
- NL-OMON38488
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 500
Inclusion Criteria
Risk of abdominal hypertension
Exclusion Criteria
< 18 years, impossibility for measuring bladder pressure
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Incidence of intra-abdominal hypertension and the abdominal compartment<br /><br>syndroom in high risk patients. Relation of certain markers (I-FABP, L-FABP,<br /><br>claudin and citruline) to intra-abdominal pressure and presence of bowel<br /><br>ischaemia. Relation of certain markers (NGAL in serum and urine) to<br /><br>intra-abdominal pressure and presence of acute kidney injury.<br /><br>Outcome of patients with intra-abdominal hypertension and abdominal compartment<br /><br>syndrome with regard to mortality, incidence of bowel ischaemia, renal<br /><br>replacement therapy (temporary/permanent), surgical procedures, length of ICU<br /><br>stay, days of ventilation, days on inotropes, number of patients with<br /><br>persistent open abdomen. </p><br>
- Secondary Outcome Measures
Name Time Method <p>not applicable</p><br>