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Clinical Trials/NCT00361686
NCT00361686
Completed
Not Applicable

Randomized Double Blind Study Comparing Patient Controlled Analgesia With Tramadol vs. Remifentanyl for Women Undergoing 2nd Trimester Abortions

Rabin Medical Center1 site in 1 country40 target enrollmentJanuary 2006

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Abortion,Induced
Sponsor
Rabin Medical Center
Enrollment
40
Locations
1
Primary Endpoint
Nausea
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

Patients undergoing second trimester abortions will recieve either patient controlled analgesia with either remifentanyl or tramadol for pain alleviation.

We beleive both to be equally effective for pain alleviation.

Detailed Description

Women undergoing second trimester abortions will recieve patient controlled analgesia eith either tramadol or remifentanyl. Patients will not know what they are recieving. Patients in the tramadol goup will get a loading dose of tramadol and metocloparamide while the women in the remifentanyl group will be given a loading placebo. Women will then be attached to one of the two patinet controlled analgesia protocols. Throughout their laboring process they will be monitored for blood pressure, pulse, breathing rate, sedation score and nausea. Additional medicatyion will be given for nausea. If woman are still in pain the patient controlled analgesia settings will be set to deliver a higher dose. If the woman remains in pain, she will be given an additional per os medication.If this still does not alleviate pain, the option of epidural analgesia will be offered.

Registry
clinicaltrials.gov
Start Date
January 2006
End Date
January 2007
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Eligibility Criteria

Inclusion Criteria

  • Woman undergoing 2nd trimester abortion -

Exclusion Criteria

  • Seizure disorder
  • \* Psychiatric disorder
  • Inability to recieve patient controlled analgesia
  • Allergy to tramadol or remifentanyl

Outcomes

Primary Outcomes

Nausea

Sedation

Satisfaction

VAS scores

Study Sites (1)

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