The Prognostic Significance of a Fragmented QRS Complex After Primary Percutaneous Coronary Intervention

Completed

• Conditions: Fragmented QRS; Primary PCI; MACE
• Interventions: Other: primary pcı

• Registration Number: NCT01136837
• Lead Sponsor: Bursa Postgraduate Hospital

Brief Summary

To investigate the prognostic significance of a fragmented QRS (fQRS) complex in a patient who had undergone primary percutaneous coronary intervention (PCI).

Detailed Description

Not available

Study Timeline

• Status Verified: 2008-11
• Study Start: 2008-11
• Primary Completion: 2009-05
• Study Completion: 2009-05
• Study First Submitted: 2010-06-02
• Study First Submitted QC: 2010-06-03
• Last Update Submitted: 2010-06-03
• Study First Posted: 2010-06-04
• Last Update Posted: 2010-06-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 85

Inclusion Criteria

• Patients with chest pain that continued longer than 30 minutes and with ≥ 2 mm ST elevation in ECG at least in two adjacent derivations were diagnosed with an acute STEMI. In all patients, at least two-fold increases were seen in serum CK-MB levels compared to normal values.Having acute STEMI for the first time was stipulated for inclusion in the study.

Exclusion Criteria

• Subjects with known allergies to aspirin and clopidogrel, inadequate echocardiographic images, malignancy, a previous cerebrovascular event, renal dysfunction (creatine level > 2.5 mg/dl), a previous MI, or a history of cardiogenic shock as well as those who refused to participate in the study were excluded.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
fragmented QRS positive	primary pcı	fQRS at 48 hours after Primary PCI

Primary Outcome Measures

Name	Time	Method
Major Adverse Cardiac Events		the presence of a fQRS at 48 hours after primary PCI is a significant parameter in predicting adverse cardiovascular events;

Secondary Outcome Measures

Name	Time	Method
Q Wave and QRS distortion for predicting major adverse cardiac events		the presence of a fQRS is a more sensitive and specific parameter in predicting development of adverse cardiovascular events than Q wave and QRS distortion; and compared to Q wave, fQRS correlated more significantly with the presence of a scar

Trial Locations

Locations (1)

Bursa Yüksek İhtisas Hastanesi; 🇹🇷 Bursa, Turkey