Outcome of Patients Who Could Not Have Been Diagnosed by Medical Thoracoscopy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 355
- 试验地点
- 1
- 主要终点
- Accuracy of medical thoracoscopy for patients diagnosed as fibrinous pleuritis.
研究概览
简要总结
Medical thoracoscopy (MT) under local anaesthetic and mild sedation, an established method in the diagnosis of pleural diseases. MT has an overall diagnostic yield above 90% for malignant pleural diseases and pleural tuberculosis. However, others who are diagnosed as fibrinous pleuritis make confusion in clinicians. Whether these patients are firmly followed or not ? The investigators do not know the answer of this question.
In this study the investigators aimed to investigate the outcome of the patients who are diagnosed as fibrinous pleuritis on MT biopsies.
详细描述
Medical thoracoscopy (MT) under local anaesthetic and mild sedation, an established method in the diagnosis of pleural diseases with a sensitivity above 90% and specificity of 1000% for malignant pleural diseases and pleural tuberculosis. Except these two groups of patients, in others pleural histopathological diagnosis is defined as "non-specific pleuritis" or "fibrinous pleuritis". Authors say that the natural evolution of these patients is poorly understood. Some of these patients was later established false negative cases for malignant pleural diseases. Clinical guidelines recommend close observation of patients with undiagnosed exudative effusions, although the length and follow-up regime is not defined, yet. In this study the investigators examine the outcome of patients who are diagnosed as fibrinous pleuritis by MT.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 85 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Undiagnosed exudative pleural effusion
- •Under 20 years-old, over 85 years-old
- •Followed 2 years at least
排除标准
- •Transudative pleural effusion
- •Patients who do not accepted medical thoracoscopy.
结局指标
主要结局
Accuracy of medical thoracoscopy for patients diagnosed as fibrinous pleuritis.
时间窗: 2 years
During 2 years after medical thoracoscopy, the diagnostic sensitivity, specificity, positive predictive value and negative predictive value are determined in the patients diagnosed as fibrinous pleuritis.
次要结局
- To determine the factors which point the false positive diagnosis of fibrinous pleuritis.(2 years)
研究者
Muzaffer Metintas
MD, Prof. in Pulmonary Medicine
Eskisehir Osmangazi University
