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临床试验/NCT01356979
NCT01356979已完成不适用

Outcome of Patients Who Could Not Have Been Diagnosed by Medical Thoracoscopy

Eskisehir Osmangazi University1 个研究点 分布在 1 个国家目标入组 355 人开始时间: 2002年2月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
355
试验地点
1
主要终点
Accuracy of medical thoracoscopy for patients diagnosed as fibrinous pleuritis.

研究概览

简要总结

Medical thoracoscopy (MT) under local anaesthetic and mild sedation, an established method in the diagnosis of pleural diseases. MT has an overall diagnostic yield above 90% for malignant pleural diseases and pleural tuberculosis. However, others who are diagnosed as fibrinous pleuritis make confusion in clinicians. Whether these patients are firmly followed or not ? The investigators do not know the answer of this question.

In this study the investigators aimed to investigate the outcome of the patients who are diagnosed as fibrinous pleuritis on MT biopsies.

详细描述

Medical thoracoscopy (MT) under local anaesthetic and mild sedation, an established method in the diagnosis of pleural diseases with a sensitivity above 90% and specificity of 1000% for malignant pleural diseases and pleural tuberculosis. Except these two groups of patients, in others pleural histopathological diagnosis is defined as "non-specific pleuritis" or "fibrinous pleuritis". Authors say that the natural evolution of these patients is poorly understood. Some of these patients was later established false negative cases for malignant pleural diseases. Clinical guidelines recommend close observation of patients with undiagnosed exudative effusions, although the length and follow-up regime is not defined, yet. In this study the investigators examine the outcome of patients who are diagnosed as fibrinous pleuritis by MT.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
20 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Undiagnosed exudative pleural effusion
  • Under 20 years-old, over 85 years-old
  • Followed 2 years at least

排除标准

  • Transudative pleural effusion
  • Patients who do not accepted medical thoracoscopy.

结局指标

主要结局

Accuracy of medical thoracoscopy for patients diagnosed as fibrinous pleuritis.

时间窗: 2 years

During 2 years after medical thoracoscopy, the diagnostic sensitivity, specificity, positive predictive value and negative predictive value are determined in the patients diagnosed as fibrinous pleuritis.

次要结局

  • To determine the factors which point the false positive diagnosis of fibrinous pleuritis.(2 years)

研究者

发起方
Eskisehir Osmangazi University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Muzaffer Metintas

MD, Prof. in Pulmonary Medicine

Eskisehir Osmangazi University

研究点 (1)

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