Effect of ANI on Intraoperative Opioid Consumption

• Conditions: Nociceptive Pain; Pain; Analgesia; Nerve Block

• Registration Number: NCT05106452
• Lead Sponsor: Zonguldak Bulent Ecevit University

Brief Summary

The aim of the study is to compare the analgesic nociception index (ANI), which is used to determine the dose of analgesic agent needed in the intraoperative period, with the conventional method in patients with erector spinae block who underwent gynecological surgery under general anesthesia.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-10-20
• Study First Submitted: 2021-10-22
• Study First Submitted QC: 2021-10-22
• Status Verified: 2021-11
• Study First Posted: 2021-11-03
• Last Update Submitted: 2021-11-04
• Last Update Posted: 2021-11-11
• Primary Completion: 2023-02-28
• Study Completion: 2023-05-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 35

Inclusion Criteria

• ASA I-II-III risk group
• Patients who underwent gynecological surgery under general anesthesia, who underwent erector spina block, and whose pain was followed by analgesia nociception index or conventional methods for intraoperative pain monitoring
• Patients whose informed consent was read and consent was obtained from them and their guardians

Exclusion Criteria

• cardiac rhythm disorder
• central-autonomic nervous system disease
• neuropsychiatric disease
• receiving opioid therapy
• Use of drugs that will affect cardiac autonomic regulation
• Known allergy to the drugs to be applied
• Contraindicated for ESP block
• Patients who do not agree to participate in the study will not be included in the study.
• Patients who were administered drugs to stabilize the patient's hemodynamics during the operation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
intraoperative opioid consumption	during the surgery	Effect of ANI monitoring on intraoperative opioid consumption

Secondary Outcome Measures

Name	Time	Method
nausea and vomiting i	during her stay in the recovery unit	incidence of nausea and vomiting in recovery room
emergence time	at the end of the surgery	time between last suture and extubation
VAS pain scores	during her stay in the recovery unit	pain scores in the recovery unit
duration of stay in recovery room	at the end of the surgery	time between entering and exiting the recovery unit

Trial Locations

Locations (1)

Zonguldak Bülent Ecevit University Medicine Faculty; 🇹🇷 Zonguldak, Kozlu, Turkey