Effect of a Health food on 2 hours Glucose Response among Overweight Individuals

Recruiting

Conditions: Male and female overweight individuals (BMI greater than or equal to 22.9)

Registration Number: CTRI/2018/04/012979

Lead Sponsor: Madras Diabetes Research Foundation

Brief Summary: Research studies have shown that lifestyle, inparticular dietary aspects play an important role in preventing / increasingthe burden of the chronic diseases. Dietary habits could therefore be modified toexert a positive impact in the prevention and treatment. It has been suggestedthat the high glycemic carbohydrate foods â€“ those foods containingcarbohydrates which elicit rapid blood glucose rise and thereby increase theinsulin demand leading to hyperinsulinemia, insulin resistance and type 2diabetes. Hence, there is a need to understand the blood glucose raisingpotential of foods in India to be of an important tool to aid in the preventionand or management of diabetes and its complication. Thus evolved the concept ofâ€˜Glycemic Indexâ€™ (GI) which ranks the foods, based on the speed at which thefood raises the blood glucose in a scale of 0 to 100, 100 indicating highglycemic index corresponds to oral glucoseâ€™s GI. Today, India leading the worldwith the largest number of diabetic volunteers causing a heavy economic burdento the country urgently need to look at cost effective strategies to combatthis situation. A cost effective dietary approach like estimating andunderstanding the role of glycemic index of various Indian foods in thelifestyle related diseases like diabetes is urgently needed. Capillary bloodglucose will be measured at 0, 15, 30, 45, 60, 90 and 120 min using HemocueGlucose 201+ analyzer (Hemocue**Â®**Ltd,Angelholm, Sweden). Standard glucose drink will be given for 3 differentdays to get average glucose response and each test food for 1 day with a washout period of 2 to 3 days between each test day. The GI was calculated as IAUCof test food/IAUC of reference (Glucose) food x 100.

Detailed Description: Not available

Recruitment & Eligibility

Status: Open to Recruitment

Sex: All

Target Recruitment: 15

Inclusion Criteria

1.BMI greater than or equal to 22.9 kg/ m2 2.Participants with family history of diabetes 3.Willingness to consume the test foods.

Exclusion Criteria

1.Underweight 2.Specific diet restriction (weight reduction, low fat, salt restriction diet) 3.Suffering from any chronic illness or medical condition (Heart disease, diabetes, high blood pressure, renal or kidney disease, anaemia) 4.Pregnant and lactating mother 5.Food allergy 6.Physically challenged.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessing the glycemic index, GI category and satiety of food products	3 months

Secondary Outcome Measures

Name	Time	Method
Assessing the proximates and available carbohydrates of food products	7 days

Trial Locations

Locations (1): Madras Diabetes Research Foundation
🇮🇳
Chennai, TAMIL NADU, India
Madras Diabetes Research Foundation
🇮🇳Chennai, TAMIL NADU, India
Dr V Mohan
Principal investigator
914439988816
drmohans@diabetes.ind.in