Investigating the effect of tranexamic acid on recovery time in patients undergoing total knee replacements

Phase 4

• Conditions: Total Knee Arthroplasty; Peri-operative bleeding with Total Knee Arthroplasty; Surgery - Other surgery

• Registration Number: ACTRN12621001327875
• Lead Sponsor: Wesley Medical Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-09-29
• Last Update Posted: 4 October 2021

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

1. Participants of either sex scheduled to undergo a primary, unilateral Total Knee Arthroplasty.
2. Available for follow up at 6 months post-surgery.
3. Willingness to provide written, informed consent.
4. Willingness to comply with the study.

Exclusion Criteria

1. Known allergy to TXA
2, Acquired disturbances to colour vision
3, Preoperative use of anticoagulants (within 5 days of surgery)
4. Fibrinolytic disorders requiring intraoperative fibrinolytics
5. Coagulopathy, history of arteriolar or venous thromboembolic disease
6. Pregnancy or breastfeeding
7. Haemoglobin <10g/dL

Study & Design

• Study Type: Interventional
• Study Design: Not specified